{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T17:04:42Z","timestamp":1792343082186,"version":"4.4.0"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Acute, chronic, and hard\u2010to\u2010heal wounds pose a growing challenge due to reduced patient quality\u2010of\u2010life, higher cost and increased hospital admissions. Although there is no gold standard for wound care, there is a trend toward simple, outpatient\u2010compatible treatment options. Acellular dermal fish skin derived from\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Gadus morhua<\/jats:italic>\n                    <\/jats:styled-content>\n                    (Atlantic cod) is a promising alternative. This retrospective study evaluated the surgical procedures and outcomes associated with fish\u2010skin graft transplantation for difficult\u2010to\u2010treat wounds. Forty\u2010four patients (33 male and 11 female; mean age: 72.4\u2009years; mean wound area: 84.5\u2009cm\n                    <jats:sup>2<\/jats:sup>\n                    ) were treated with acellular fish skin graft. Wound healing was assessed by photographic documentation, confocal microscopy and clinical evaluation. Patient satisfaction was assessed using a structured questionnaire. A positive effect on wound healing, defined as a reduction in wound size, was observed in 88.6% of cases, with complete wound closure in 45.45% of cases. Most patients reported that the procedure was neither painful nor time\u2010intensive; 95% stated that they would opt for treatment again. Fish skin grafting has also shown beneficial outcomes in complex cases, such as in wounds secondary to pyoderma gangrenosum and wounds with exposed bone. Fish skin graft transplantation represents a safe, well\u2010tolerated and effective option for managing chronic wounds as well as challenging postoperative wounds, such as those at anatomically challenging sites.\n                  <\/jats:p>","DOI":"10.1111\/iwj.70931","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:31:14Z","timestamp":1777336274000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of Acellular Intact Fish Skin Grafts for Treating Acute and Chronic Wounds"],"prefix":"10.1111","volume":"23","author":[{"given":"Christopher","family":"B\u00f6ddeker","sequence":"first","affiliation":[{"name":"Department of Dermatology University Hospital Duesseldorf, Medical Faculty, Heinrich\u2010Heine\u2010University Duesseldorf  Duesseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Biermann","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Duesseldorf, Medical Faculty, Heinrich\u2010Heine\u2010University Duesseldorf  Duesseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa Maria","family":"Jansen","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Duesseldorf, Medical Faculty, Heinrich\u2010Heine\u2010University Duesseldorf  Duesseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Homey","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Duesseldorf, Medical Faculty, Heinrich\u2010Heine\u2010University Duesseldorf  Duesseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norman\u2010Philipp","family":"Hoff","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Duesseldorf, Medical Faculty, Heinrich\u2010Heine\u2010University Duesseldorf  Duesseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.15087"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers17071113"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2010.07535.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2024.09.024"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.04.020"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15322"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2018.27.Sup6a.S1"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2024.110041"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1534734615573661"},{"key":"e_1_2_10_11_1","first-page":"112","article-title":"A Prospective, Postmarket, Compassionate Clinical Evaluation of a Novel Acellular Fish\u2010Skin Graft Which Contains Omega\u20103 Fatty Acids for the Closure of Hard\u2010To\u2010Heal Lower Extremity Chronic Ulcers","volume":"28","author":"Yang C. 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Medicina (Kaunas)"},{"key":"e_1_2_10_23_1","first-page":"262","article-title":"Acellular Fish Skin Graft Use for Diabetic Lower Extremity Wound Healing: A Retrospective Study of 58 Ulcerations and a Literature Review","volume":"31","author":"Michael S.","year":"2019","journal-title":"Wounds"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2025.101691"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.70847"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12761"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1088\/1748-605X\/abef7a"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0846.2012.00623.x"}],"container-title":["International Wound Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.70931","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/iwj.70931","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.70931","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T03:46:29Z","timestamp":1779680789000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iwj.70931"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,27]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1111\/iwj.70931"],"URL":"https:\/\/doi.org\/10.1111\/iwj.70931","archive":["Portico"],"relation":{},"ISSN":["1742-4801","1742-481X"],"issn-type":[{"value":"1742-4801","type":"print"},{"value":"1742-481X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,27]]},"assertion":[{"value":"2026-01-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70931"}}