{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T11:11:20Z","timestamp":1790334680073,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T00:00:00Z","timestamp":1789344000000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Hyperbaric oxygen therapy (HBOT) is an established adjunctive treatment for selected diabetic foot ulcers, although evidence regarding its effectiveness remains heterogeneous. We conducted a retrospective, single\u2010center, observational study of adult diabetic patients receiving HBOT (2.5 ATA, 100% oxygen) for a lower\u2010limb wound at the only hyperbaric center in Guadeloupe, a French Caribbean territory, between January 2020 and June 2023. Among 257 patients treated with HBOT, 71 diabetic patients met inclusion criteria (mean age 63.1\u2009\u00b1\u200912.7\u2009years; 69% male). Peripheral arterial disease and osteitis were highly prevalent, while the proportion of current smokers (7.9%) was notably lower than in previously published HBOT cohorts, a distinctive feature of this population. HBOT was considered a last resort, after failure of prolonged conventional therapy, in 63% of patients, likely contributing to the modest six\u2010month healing rate of 34% (18\/53 evaluable patients) and 19% rate of major amputation occurring during or after HBOT. Patients referred through the multidisciplinary Diabetic Foot Care Unit had fewer major amputations despite older age and greater vascular burden, though this comparison may reflect referral\u2010related selection bias. No candidate factor, including glycemic control, referral pathway, or delay to HBOT, reached statistical significance in univariable analysis. This descriptive, single\u2010arm finding cannot establish HBOT efficacy but is consistent with a role for HBOT within coordinated multidisciplinary diabetic foot care, highlighting the importance of earlier referral and optimised patient selection.<\/jats:p>","DOI":"10.1111\/iwj.71040","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T05:11:26Z","timestamp":1789449086000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hyperbaric Oxygen Therapy for Diabetic Lower\u2010Limb Wounds in the Caribbean: A Retrospective Cohort Study"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5026-0462","authenticated-orcid":false,"given":"Van\u00e9va","family":"Chingan Martino","sequence":"first","affiliation":[{"name":"Diabetic Foot Unit University Hospital of Guadeloupe  Pointe\u2010\u00e0\u2010Pitre France"},{"name":"Caribbean Clinical Investigation Center, Inserm CIC 2504 University Hospital of Guadeloupe  Pointe\u2010\u00e0\u2010Pitre Guadeloupe France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Pusel","sequence":"additional","affiliation":[{"name":"Diabetic Foot Unit University Hospital of Guadeloupe  Pointe\u2010\u00e0\u2010Pitre France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djamel","family":"Bouamama","sequence":"additional","affiliation":[{"name":"Medical Informatics Department University Hospital of Guadeloupe  Pointe\u2010\u00e0\u2010Pitre France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7578-9259","authenticated-orcid":false,"given":"Dominique","family":"Gibert","sequence":"additional","affiliation":[{"name":"LGL\u2010TPE, Univ Lyon, Univ Lyon 1, ENSL, CNRS, UMR 5276  Villeurbanne France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Cheret","sequence":"additional","affiliation":[{"name":"University of French West Indies, INSERM\u2010CIC\u20101424, Centre Hospitalier Universitaire  Pointe\u2010\u00e0\u2010Pitre France"},{"name":"University Hospital of Guadeloupe, Service Plateforme de Diagnostic et Th\u00e9rapeutique Pluridisciplinaire  Pointe\u2010\u00e0\u2010Pitre France"},{"name":"Institut Cochin, Universit\u00e9 Paris Descartes, Inserm U1016, CNRS UMR 8104  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1615439"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2016.1231932"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125\u2010008\u20101089\u20106"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125\u2010022\u201005845\u20109"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3266"},{"key":"e_1_2_10_7_1","unstructured":"F.GameandW.Jeffcoate \u201cGuidelines on Diabetic Foot Care 2023 \u201dInternational Working Group on the Diabetic Foot (IWGDF) [Internet] (2023) https:\/\/iwgdfguidelines.org\/guidelines\/."},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.4239\/wjd.v13.i12.1014"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1086\/511036"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmrj.2009.03.012"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102019\u2010031708"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40200\u2010021\u201000891\u20103"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.asjsur.2021.07.047"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc15\u20102001"},{"key":"e_1_2_10_15_1","volume-title":"Surveillance du diab\u00e8te en Guadeloupe: donn\u00e9es 2022","author":"Sant\u00e9 publique France","year":"2022"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2018.30.100.14826"},{"issue":"2","key":"e_1_2_10_17_1","first-page":"83","article-title":"Effects of Smoking on Cost and Duration of Hyperbaric Oxygen Therapy for Diabetic Patients With Non\u2010Healing Wounds","volume":"27","author":"Otto G. 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