{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T07:51:59Z","timestamp":1791532319242,"version":"4.3.4"},"reference-count":21,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>To determine whether heel\u2010free compression bandaging is non\u2010inferior to heel\u2010wrapped bandaging for maintaining interface pressure in adults with venous leg ulcers. Randomised, controlled, parallel\u2010group, non\u2010inferiority trial. Adults with open venous leg ulcers (CEAP C6) treated at a French university hospital were randomised to heel\u2010free or heel\u2010wrapped (control) bandaging for 4\u20136\u2009weeks. The primary outcome was interface pressure 48\u2009h after the final bandage application, analysed in the per\u2010protocol population. Secondary outcomes were ankle oedema, change in interface pressure and patient preference. Of 102 randomised patients, 85 were included in the per\u2010protocol analysis. At V3, mean interface pressure was 30.1\u2009mmHg in the heel\u2010free group and 28.4\u2009mmHg in the control group (difference, 1.7\u2009mmHg; 95% CI, \u22121.3 to 4.6), meeting the non\u2010inferiority criterion. After adjustment for baseline circumference and sex, ankle circumference was 1.7\u2009cm lower in the heel\u2010free group (95% CI, \u22123.35 to 0.04). Among 48 patients who had experienced both techniques, 23 (47.9%) preferred heel\u2010free bandaging. Heel\u2010free bandaging was non\u2010inferior to heel\u2010wrapped bandaging for interface pressure at 48\u2009h. The technique may be considered when compatible with ulcer location and patient preference; effects on healing and adherence require further study.<\/jats:p>\n                  <jats:p>\n                    <jats:bold>Trial Registration:<\/jats:bold>\n                    NCT04046120.\n                  <\/jats:p>","DOI":"10.1111\/iwj.71052","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T07:46:17Z","timestamp":1791531977000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Heel\u2010Free Compression Bandaging for Venous Leg Ulcers: A Non\u2010Inferiority Trial of Interface Pressure"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5623-2245","authenticated-orcid":false,"given":"Anne","family":"Mauvilain","sequence":"first","affiliation":[{"name":"Mobile Vascular Wounds Unit Nantes Universit\u00e9, CHU Nantes  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Durant","sequence":"additional","affiliation":[{"name":"Internal Medicine Department Nantes Universit\u00e9, CHU Nantes  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-5191-6243","authenticated-orcid":false,"given":"Annastasia","family":"Voisine","sequence":"additional","affiliation":[{"name":"Nantes Universit\u00e9, CHU Nantes  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3701-6693","authenticated-orcid":false,"given":"Bastien","family":"Perrot","sequence":"additional","affiliation":[{"name":"INSERM Research Unit UMR 1246 (Methods in Patient\u2010Centred Outcomes and Health Research, SPHERE) Nantes University, Nantes, France; Tours University  Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4253-9939","authenticated-orcid":false,"given":"Emmanuelle","family":"Cartron","sequence":"additional","affiliation":[{"name":"Nursing Department Universit\u00e9 Paris Cit\u00e9, Inserm, ECEVE  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000265"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2023.08.011"},{"key":"e_1_2_11_4_1","unstructured":"Haute autorit\u00e9 de sant\u00e9 \u201cPrise en Charge de L'ulc\u00e8re de Jambe \u00e0 Pr\u00e9dominance Veineuse Hors Pansement 2006\u201d."},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105\u2010020\u201004706\u2010z"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102648.2006.03816.x"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2009.10.042"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13891"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742\u2010481X.2009.00621.x"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0268355520909066"},{"key":"e_1_2_11_11_1","unstructured":"Soci\u00e9t\u00e9 fran\u00e7aise de m\u00e9decine vasculaire \u201cGuide de la Compression \u201dLa lettre du m\u00e9decin vasculaire 2022."},{"key":"e_1_2_11_12_1","unstructured":"RNAO \u201cAssessment and Management of Venous Leg Ulcers 2007\u201d."},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.3917\/rsi.137.0091"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jan.15608"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2004.09.027"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000365111"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1510063"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.1979.1.1.51"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rehab.2014.06.005"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524\u20104725.2006.32039.x"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742\u2010481X.2011.00819.x"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2017.06.017"}],"container-title":["International Wound Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.71052","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/iwj.71052","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iwj.71052","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T07:46:19Z","timestamp":1791531979000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iwj.71052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":21,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1111\/iwj.71052"],"URL":"https:\/\/doi.org\/10.1111\/iwj.71052","archive":["Portico"],"relation":{},"ISSN":["1742-4801","1742-481X"],"issn-type":[{"value":"1742-4801","type":"print"},{"value":"1742-481X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"2026-02-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71052"}}