{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T20:20:58Z","timestamp":1778876458349,"version":"3.51.4"},"reference-count":10,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,2,19]],"date-time":"2004-02-19T00:00:00Z","timestamp":1077148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Anaesthesiol Scand"],"published-print":{"date-parts":[[2004,3]]},"abstract":"<jats:p>We report a case presenting with massive overdose of hydroxychloroquine who survived without any sequelae. A 17\u2010year\u2010old girl presented to the Emergency Department 45\u2003min after the ingestion of 22\u2003g of hydroxychloroquine in a suicide attempt. We believe this is highest dose yet reported in the medical literature. The patient developed hypotension, life\u2010threatening ventricular arrhythmias and mild hypokalemia. She was managed with saline infusion and dopamine for hypotension, gastric lavage and activated charcoal for decontamination, lidocain, magnesium sulfate and defibrillation for pulseless ventricular tachycardia. Potassium replacement and bicarbonate administration were performed. Quick treatment of hypotension, gastric decontamination, continuous long\u2010term cardiac monitoring, and treatment of arrhythmias are the cornerstones of hydroxychloroquine overdose management.<\/jats:p>","DOI":"10.1111\/j.0001-5172.2004.0302.x","type":"journal-article","created":{"date-parts":[[2004,2,19]],"date-time":"2004-02-19T14:36:28Z","timestamp":1077201388000},"page":"379-381","source":"Crossref","is-referenced-by-count":35,"title":["Massive hydroxychloroquine overdose"],"prefix":"10.1111","volume":"48","author":[{"given":"S.","family":"Yanturali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Aksay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O. F.","family":"Demir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Atilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,2,19]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1081\/CLT-100102466"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/ajem.2001.25774"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1053\/ajem.2002.33775"},{"key":"e_1_2_6_5_2","first-page":"582","article-title":"Severe hydroxychloroquine poisoning reversed with diazepam [abstract]","volume":"33","author":"Pruchnicki SA","year":"1996","journal-title":"J Toxicol Clin Toxicol"},{"issue":"50","key":"e_1_2_6_6_2","first-page":"2445","article-title":"A patient with acute hydroxycholoroquine poisoning: recommendation for treatment","volume":"134","author":"Strakova Z","year":"1990","journal-title":"Ned Tijdschr Geneeskd"},{"key":"e_1_2_6_7_2","first-page":"504","volume-title":"Pharm J","author":"Anonymous.","year":"1963"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)92711-5"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1990.tb14629.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.3109\/15563658308990070"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00256764"}],"container-title":["Acta Anaesthesiologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.0001-5172.2004.0302.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.0001-5172.2004.0302.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T11:18:45Z","timestamp":1697455125000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.0001-5172.2004.0302.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,2,19]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["10.1111\/j.0001-5172.2004.0302.x"],"URL":"https:\/\/doi.org\/10.1111\/j.0001-5172.2004.0302.x","archive":["Portico"],"relation":{},"ISSN":["0001-5172","1399-6576"],"issn-type":[{"value":"0001-5172","type":"print"},{"value":"1399-6576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,2,19]]}}}