{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:53:27Z","timestamp":1787014407078,"version":"build-2736575974"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,2,16]],"date-time":"2005-02-16T00:00:00Z","timestamp":1108512000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Obstet Gynecol Scand"],"published-print":{"date-parts":[[2005,3]]},"abstract":"<jats:p>\n                    <jats:bold>Objective.\u2002<\/jats:bold>\n                    To produce normograms of Doppler indices of major fetal arteries and their ratios relative to the ascending aorta in a cohort of appropriately grown for gestational age fetuses.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods.\u2002<\/jats:bold>\n                    Prospective longitudinal study of 70 women with appropriately grown for gestational age fetuses between 24 and 38\u2003weeks' gestation attending the Fetal Growth Clinic of a large UK teaching hospital. Doppler velocimetry of the middle cerebral (MCA), umbilical (UmA) and renal arteries (RA) and the ascending (AAO) and descending (DAO) aortas were studied using color power angiography. Ratios of the Doppler indices [pulsatility index (PI), resistance index (RI), systolic\/diastolic (S\/D) ratio] were then calculated using the ascending aorta as the reference numerator for the other four vessels to produce normograms. Regression analysis was performed to determined the significance, if any, of the changes in these ratios with gestation.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results.\u2002<\/jats:bold>\n                    The normograms of the various Doppler indices were similar for the middle cerebral artery, ascending and descending aortas. There was an initial rise to a peak between 30 and 32\u2003weeks and then a gradual return to values at 38\u2003weeks similar to those at 24\u2003weeks' gestation. In the renal artery, the indices showed very little variation with gestation. However, there was a gradual fall in the indices with gestation in the umbilical artery. The ratios of the various indices relative to that of the ascending aorta demonstrated an increase with gestation. The changes with gestation were statistically significant for the ratios of the indices from the ascending aorta to those of the middle cerebral, renal and umbilical arteries but not for those of the descending aorta.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions.\u2002<\/jats:bold>\n                    The vascular resistance in the five fetal arteries decreased towards the end of pregnancy and the ratios of their indices relative to those of the ascending aorta decreased from 24 to 38\u2003weeks' gestation. Early subtle changes in circulation in compromised fetuses may be identified early from deviations in these normograms.\n                  <\/jats:p>","DOI":"10.1111\/j.0001-6349.2005.00549.x","type":"journal-article","created":{"date-parts":[[2005,2,16]],"date-time":"2005-02-16T17:43:01Z","timestamp":1108575781000},"page":"230-237","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Normative values of Doppler velocimetry of five major fetal arteries as determined by color power angiography"],"prefix":"10.1111","volume":"84","author":[{"given":"Justin C.","family":"Konje","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith R.","family":"Abrams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,2,16]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6100.1450"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1980.tb04613.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1159\/000263274"},{"key":"e_1_2_5_5_2","first-page":"705","article-title":"Cerebral and umbilical artery flow velocity waveforms in normal and growth retarded pregnancies","volume":"69","author":"Wladimiroff JW","year":"1987","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-3782(88)90058-8"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1989.tb03326.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S0002-9378(16)32989-1","article-title":"Blood flow to fetal organs as a function of arterial oxygen content","volume":"135","author":"Peters LLH","year":"1979","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)90833-S"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1990.tb02573.x"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)90003-1"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1991.tb15332.x"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(95)90466-2"},{"key":"e_1_2_5_14_2","volume-title":"Pregnancy and Childbirth Module of the Cochrane Database of Systematic Reviews. The Cochrane Library, The Cochrane Collaboration, Issue I.","author":"Neilson JP","year":"1998"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)92490-7"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1993.tb15207.x"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(94)70226-8"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1515\/jpme.1991.19.1-2.21"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(89)90257-3"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1515\/jpme.1992.20.1.29"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1999.13060407.x"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1515\/jpme.1990.18.3.165"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(00)70230-4"},{"key":"e_1_2_5_24_2","first-page":"78","article-title":"Improved prediction of pre\u2010eclampsia by two\u2010stage screening of the uterine arteries using the early diastolic notch and color Doppler imaging","volume":"82","author":"Bower S","year":"1993","journal-title":"Obstet Gynecol"},{"key":"e_1_2_5_25_2","first-page":"27","article-title":"Screening for placental insufficiency by uterine artery Doppler","volume":"6","author":"Papageorghiou AT","year":"2001","journal-title":"Prenat Neonat Med"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2000.00217.x"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.307.6904.588"},{"key":"e_1_2_5_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1984.tb05891.x"},{"key":"e_1_2_5_29_2","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1991.10.6.331"},{"key":"e_1_2_5_30_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1992.02040272.x"},{"key":"e_1_2_5_31_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1995.06010019.x"}],"container-title":["Acta Obstetricia et Gynecologica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.0001-6349.2005.00549.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.0001-6349.2005.00549.x","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.0001-6349.2005.00549.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T16:49:51Z","timestamp":1696956591000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/j.0001-6349.2005.00549.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2,16]]},"references-count":30,"aliases":["10.1080\/j.0001-6349.2005.00549.x"],"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["10.1111\/j.0001-6349.2005.00549.x"],"URL":"https:\/\/doi.org\/10.1111\/j.0001-6349.2005.00549.x","archive":["Portico"],"relation":{},"ISSN":["0001-6349","1600-0412"],"issn-type":[{"value":"0001-6349","type":"print"},{"value":"1600-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,2,16]]},"assertion":[{"value":"2005-02-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}