{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:02:24Z","timestamp":1760979744326},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,9,1]],"date-time":"2004-09-01T00:00:00Z","timestamp":1093996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Australasian Radiology"],"published-print":{"date-parts":[[2004,9]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The purpose of the present paper was to evaluate the utility of perfusion MRI in cerebral gliomas showing imperceptible contrast enhancement on conventional MRI, and to evaluate the relationships of perfusion MRI and magnetic resonance (MR) spectroscopic results in these tumours. Twenty\u2010two patients with histopathologically proven cerebral gliomas and showing insignificant contrast enhancement on conventional MR were included in the present study. All patients underwent perfusion MRI and MR spectroscopy on a 1.5\u2010T MR system. Significant differences of the relative cerebral blood volume (rCBV) values and the choline\u2003:\u2003creatine ratios were noted between low\u2010grade and anaplastic gliomas (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.01). Good correlation was found between the rCBV values and the choline\u2003:\u2003creatine values (<jats:italic>y<\/jats:italic>\u2003=\u20030. 532x\u2003+\u20031.5643; <jats:italic>r<\/jats:italic>\u2003=\u20030.67). Perfusion MRI can be a useful tool in assessing the histopathological grade of non\u2010contrast\u2010enhancing cerebral gliomas. Along with MR spectroscopic imaging it can serve as an important technique for preoperative characterization of such gliomas, so that accurate targeting by stereotactic biopsies is possible.<\/jats:p>","DOI":"10.1111\/j.0004-8461.2004.01315.x","type":"journal-article","created":{"date-parts":[[2004,9,1]],"date-time":"2004-09-01T14:56:59Z","timestamp":1094050619000},"page":"324-332","source":"Crossref","is-referenced-by-count":25,"title":["Perfusion magnetic resonance imaging and magnetic resonance spectroscopy of cerebral gliomas showing imperceptible contrast enhancement on conventional magnetic resonance 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