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Recent immunoepidemiological data implicate T<\/jats:italic><jats:sub><jats:italic><jats:sc>h<\/jats:sc><\/jats:italic><\/jats:sub><jats:italic>2\u2010mediated responses in limiting<\/jats:italic> A.\u00a0lumbricoides <jats:italic>and<\/jats:italic> T.\u00a0trichiura <jats:italic>populations. Reinfection studies further suggest that IL\u20105 cytokine responses are negatively associated with adult recruitment in<\/jats:italic> T.\u00a0trichiura <jats:italic>but not<\/jats:italic> A.\u00a0lumbricoides<jats:italic> and may therefore be involved in negative intraspecific and interspecific interactions mediated through the host immune system. The importance of inducible immunoregulatory networks in the ecology of the host\u2013parasite relationship is considered, with particular regard to possible manipulative strategies by the parasites. 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