{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:12:05Z","timestamp":1761862325711},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,2,6]],"date-time":"2004-02-06T00:00:00Z","timestamp":1076025600000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2004,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim\u2002<\/jats:bold> To report on an unusual case of gingival necrosis following the use of a paraformaldehyde\u2010containing paste in root canal treatment.<\/jats:p><jats:p><jats:bold>Summary\u2002<\/jats:bold> Paraformaldehyde preparations are toxic to hard and soft tissues. In an era of effective local anaesthesia, toxic devitalizing preparations have few applications. However, in a mobile world population, severe tissue injury may occasionally be encountered after the use of paraformaldehyde or other toxic agents in some parts of the world. Dentists should avoid such preparations and be alert of the features and management of local toxicity if they encounter it in practice.<\/jats:p><jats:p><jats:bold>Key learning points\u2002<\/jats:bold> \n<jats:list list-type=\"explicit-label\">\n<jats:list-item><jats:p>Paraformaldehyde\u2010containing pastes have no application in contemporary dentistry.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Dentists should avoid toxic preparations for pulp devitalization.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Dentists should be aware of the features and management of tissue necrosis resulting from the use of toxic dressing materials.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p>","DOI":"10.1111\/j.0143-2885.2004.00770.x","type":"journal-article","created":{"date-parts":[[2004,2,6]],"date-time":"2004-02-06T14:18:58Z","timestamp":1076077138000},"page":"157-161","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Gingival necrosis following the use of a paraformaldehyde\u2010containing paste: a case 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