{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T22:51:44Z","timestamp":1763765504367},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,12,15]],"date-time":"2004-12-15T00:00:00Z","timestamp":1103068800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:p><jats:bold>Background:\u2002<\/jats:bold> Nevi on certain areas of the body such as the acral, genital, and flexural regions may exhibit uncommon but characteristic histopathologic features. The purpose of this study was to characterize the distinctive features of nevi with a junctional component located on and around the ear.<\/jats:p><jats:p><jats:bold>Materials and methods:\u2002<\/jats:bold> A total of 101 compound and junctional nevi of the ear received at the Yale Dermatopathology Laboratory during a 10\u2010year period were examined in this study. The most characteristic feature of the majority of these nevi was irregularity of nesting pattern, with nests, which varied in size and shape and which were sometimes located between rete ridges.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Forty\u2010two (42%) of nevi on and around the ear showed poor circumscription, lateral extension of the junctional component beyond the dermal component, and elongation of rete ridges with bridging between them. A subset of these nevi (26 cases) showed uniformly large melanocytes with large vesicular nuclei without prominent nucleoli, and abundant pale, finely granular cytoplasm. These lesions did not show a tendency to recur.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> This study supports the existence of a subset of nevi on or near the ear that, like certain nevi located on other special sites, exhibit unusual but characteristic features, which may be misinterpreted as atypical or malignant.<\/jats:p>","DOI":"10.1111\/j.0303-6987.2005.00263.x","type":"journal-article","created":{"date-parts":[[2004,12,15]],"date-time":"2004-12-15T14:27:05Z","timestamp":1103120825000},"page":"40-44","source":"Crossref","is-referenced-by-count":41,"title":["The characteristic histopathologic features of nevi on and around the ear"],"prefix":"10.1111","volume":"32","author":[{"given":"Rossitza","family":"Lazova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Lester","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Earl J.","family":"Glusac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamara","family":"Handerson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"McNiff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,12,15]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.1999.00672.x"},{"key":"e_1_2_5_3_2","first-page":"1117","article-title":"The natural history of the pigmented nevus: factors of age and anatomic location","volume":"25","author":"Lund HZ","year":"1949","journal-title":"Am J Pathol"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(94)70235-7"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1995.tb00326.x"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s100249900053"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1998.tb02340.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1994.tb00555.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199903000-00006"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1996.tb03994.x"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199507000-00007"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199202000-00076"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.3109\/00313028409068542"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-200204000-00017"},{"key":"e_1_2_5_15_2","first-page":"159","article-title":"Differentiation of melanocytic nevi from malignant melanomas in palms, soles and nail beds solely by signs in the cornified layer of the epidermis","volume":"6","author":"Kerl H","year":"1984","journal-title":"Am J Dermatopathol"},{"key":"e_1_2_5_16_2","first-page":"378","article-title":"Melanocytic acral nevi with intraepidermal ascent of cells (MANIACs): a reappraisal of melanocytic nevi from acral sites","volume":"18","author":"McCalmont TH","year":"1991","journal-title":"J Cutan Pathol"},{"key":"e_1_2_5_17_2","first-page":"119","volume-title":"Pathology of malignant melanoma","author":"Friedman RJ","year":"1981"},{"key":"e_1_2_5_18_2","first-page":"366","article-title":"Atypical melanocytic lesions of the vulva","volume":"15","author":"Jampel RM","year":"1988","journal-title":"J Cutan Pathol"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1987.tb00478.x"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(98)90381-1"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0560.2000.027005215.x"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.50.1.7"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0007-1226(90)90129-N"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-5182(05)80256-2"},{"key":"e_1_2_5_25_2","first-page":"661","article-title":"Malignant melanoma of the head and neck in Scotland: an eight\u2010year analysis of trends in prevalence, distribution and prognosis","volume":"64","author":"Cox NH","year":"1987","journal-title":"Q J Med"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198412000-00017"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(80)90203-2"},{"key":"e_1_2_5_28_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100124466"},{"key":"e_1_2_5_29_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19880815)62:4<831::AID-CNCR2820620432>3.0.CO;2-X"},{"key":"e_1_2_5_30_2","first-page":"431","volume-title":"Tumours of the head and neck. 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