{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T15:10:17Z","timestamp":1777648217807,"version":"3.51.4"},"reference-count":52,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,2,8]],"date-time":"2005-02-08T00:00:00Z","timestamp":1107820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Cutan Pathol"],"published-print":{"date-parts":[[2005,3]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> Erythema induratum (EI)\/nodular vasculitis (NV) is characterized by recurrent crops of tender oedematous nodules on the lower legs. A lobular panniculitis with granulomatous inflammation, vasculitis, focal necrosis and septal fibrosis is present. <jats:italic>Mycobacterium tuberculosis<\/jats:italic> DNA has been detected in some lesions by means of polymerase chain reaction (PCR). Ten cases of EI\/NV were found. H&amp;E slides were reviewed. PCR assays for <jats:italic>M. tuberculosis<\/jats:italic> and mycobacteria other than <jats:italic>M. tuberculosis<\/jats:italic> (MOTT) were performed. PCR did not reveal <jats:italic>M. tuberculosis<\/jats:italic> (0%) or MOTT (0%) DNA, with positive controls, indicating the reliability of the assays. Among the MOTT, cutaneous infections are most commonly caused by <jats:italic>M. marinum<\/jats:italic>. Subcutaneous tuberculoid granulomas may be seen with <jats:italic>M. kansasii<\/jats:italic>, <jats:italic>M. marinum<\/jats:italic>, <jats:italic>M. scrofulaceum<\/jats:italic> and <jats:italic>M. avium<\/jats:italic> complex. <jats:italic>M. gordonae<\/jats:italic>, <jats:italic>M. szulgai<\/jats:italic> and <jats:italic>M. malmoense<\/jats:italic> rarely cause cutaneous infections. <jats:italic>M. simiae<\/jats:italic>, <jats:italic>M. gastri<\/jats:italic> and <jats:italic>M. asiaticum<\/jats:italic> are probably not cutaneous pathogens. <jats:italic>M. tuberculosis<\/jats:italic> and MOTT DNA was not found in EI\/NV. EI\/NV has diverse aetiologies with varying pathogeneses leading to similar histologic changes. The cases analysed may not have had an infectious aetiology. However, in EI\/NV, performance of PCR for MOTT as well as <jats:italic>M. tuberculosis<\/jats:italic> complex may still be beneficial, particularly in cases from immunocompromised hosts.<\/jats:p>","DOI":"10.1111\/j.0303-6987.2005.00296.x","type":"journal-article","created":{"date-parts":[[2005,2,8]],"date-time":"2005-02-08T10:41:23Z","timestamp":1107859283000},"page":"220-226","source":"Crossref","is-referenced-by-count":22,"title":["Mycobacteria other than <i>Mycobacterium tuberculosis<\/i> are not present in erythema induratum\/nodular vasculitis: a case series and literature review of the clinical and histologic findings"],"prefix":"10.1111","volume":"32","author":[{"given":"Ilene B.","family":"Bayer\u2010Garner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark D.","family":"Cox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margie 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