{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T00:01:56Z","timestamp":1773446516808,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T00:00:00Z","timestamp":1172102400000},"content-version":"vor","delay-in-days":1513,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Progress Cardiovascular Nurs"],"published-print":{"date-parts":[[2003,1]]},"abstract":"<jats:p> <jats:italic>Prevention of cardiovascular disease must begin in childhood, preferably before risk factors develop. Elevated low\u2010density lipoprotein cholesterol levels in children are likely to track over time and become high\u2010risk levels in adults. The Dietary Intervention Study in Children (DISC) was a multicenter, collaborative randomized trial in preadolescent children designed to test the efficacy and safety of a dietary intervention to lower saturated fat and cholesterol intake among growing children with elevated low\u2010density lipoprotein cholesterol. Numerous DISC results, which include findings on lipids\u2010lipoproteins, genetics, and nutrient adequacy, as well as descriptions of the behavioral intervention strategies, have been reported. A summary of practical findings and their potential clinical applications have not previously been published. Highlights of key lessons learned from DISC and translational applications of potential interest to nurses and other health care providers are presented.<\/jats:italic> <\/jats:p>","DOI":"10.1111\/j.0889-7204.2003.01007.x","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T13:18:37Z","timestamp":1172150317000},"page":"28-41","source":"Crossref","is-referenced-by-count":28,"title":["A Summary of Results of the Dietary Intervention Study in Children (DISC): Lessons Learned"],"prefix":"10.1111","volume":"18","author":[{"given":"Horn","family":"Linda Van","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Obarzanek","family":"Eva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barton","family":"Bruce A.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stevens","family":"Victor J.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwiterovich","family":"Peter O.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lasser","family":"Norman L.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robson","family":"Alan M.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Franklin","family":"Frank A.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauer","family":"Ronald M.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimm","family":"Sue Y.S.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorgan","family":"Joanne F.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greenlick","family":"Merwyn R.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,2,22]]},"reference":[{"issue":"3","key":"e_1_2_11_2_2","first-page":"525","article-title":"National Cholesterol Education Program: report of the Expert Panel on Blood Cholesterol Levels in Children and Adolescents","volume":"89","author":"American Academy of Pediatrics","year":"1992","journal-title":"Pediatrics"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/1047-2797(93)90067-E"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.273.18.1429"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.107.2.256"},{"key":"e_1_2_11_6_2","volume-title":"Growth at Adolescence: With a General Consideration of the Effects of Hereditary and Environmental Factors Upon Growth and Maturation from Birth to Maturity","author":"Tanner JM","year":"1962"},{"key":"e_1_2_11_7_2","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/S0002-8223(21)01536-4","article-title":"Dietary assessment in children using electronic methods; 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