{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T09:10:26Z","timestamp":1759741826559},"reference-count":50,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2004,6,25]],"date-time":"2004-06-25T00:00:00Z","timestamp":1088121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2004,7]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> Psoriasis is a chronic inflammatory skin disease that is known to have a strong genetic predisposition. Several psoriasis\u2010susceptibility loci have been previously found through genomic scans. Of these, psoriasis\u2010susceptibility region 1 (<jats:italic>PSORS1<\/jats:italic>) on chromosome 6p21 remains the most consistently identified region across populations with the highest association with disease. <jats:italic>STG<\/jats:italic> is a gene that was previously isolated from rhesus monkey taste buds, and its ortholog in humans was found to be part of the cluster of genes in <jats:italic>PSORS1<\/jats:italic>, which is telomeric to HLA\u2010C. Upon characterization of <jats:italic>STG<\/jats:italic>, we identified several sequence variants and investigated their association with psoriasis in cases and controls from the Swedish population. None of these <jats:italic>STG<\/jats:italic> single\u2010nucleotide polymorphisms were found to be significantly associated with psoriasis. However, HLA\u2010Cw*0602 status was strongly associated with disease. <jats:italic>STG<\/jats:italic> expression was investigated in human tissues and found not to be restricted to taste buds, with signals also being detected in skin and tonsils.<\/jats:p>","DOI":"10.1111\/j.0906-6705.2004.00170.x","type":"journal-article","created":{"date-parts":[[2004,6,25]],"date-time":"2004-06-25T08:04:05Z","timestamp":1088150645000},"page":"413-418","source":"Crossref","is-referenced-by-count":10,"title":["<i>STG<\/i> does not associate with psoriasis in the Swedish population"],"prefix":"10.1111","volume":"13","author":[{"given":"Fabio","family":"S\u00e1nchez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofia 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