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This study was performed to exploit DC migration in the elicitation phase in a mouse model of allergic contact dermatitis and to evaluate the effects of steroidal and non\u2010steroidal anti\u2010inflammatory drugs (NSAIDs) on DC migration through skin in the elicitation phase of allergic contact dermatitis. Topically and systemically administered acetylsalicylic acid (ASA) did not reduce the inflammatory response. However, systemically administered ASA significantly reduced the DC migration to the draining lymph node. In contrast, topically administered indomethacin reduced the inflammatory response, but had only minor effects on DC migration, whereas diflorasone diacetate reduced both inflammatory reaction and DC migration. Thus, NSAIDs may differ in their inhibitory action in immunological inflammation.<\/jats:p>","DOI":"10.1111\/j.0906-6705.2006.00412.x","type":"journal-article","created":{"date-parts":[[2006,3,2]],"date-time":"2006-03-02T14:10:27Z","timestamp":1141308627000},"page":"322-329","source":"Crossref","is-referenced-by-count":17,"title":["Non\u2010steroidal and steroidal anti\u2010inflammatory drugs vary in their modulation of dendritic cell function in the elicitation phase of allergic contact dermatitis"],"prefix":"10.1111","volume":"15","author":[{"given":"W.","family":"B\u00e4umer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Krekeler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. 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