{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T10:54:28Z","timestamp":1768906468586,"version":"3.49.0"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2004,9,16]],"date-time":"2004-09-16T00:00:00Z","timestamp":1095292800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["resjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Insect Molecular Biology"],"published-print":{"date-parts":[[2004,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The sterol carrier protein\u2010x (SCP\u2010x), a peroxisomal thiolase\/nonspecific lipid binding protein, was characterized in the yellow fever mosquito,\n                    <jats:italic>Aedes aegypti<\/jats:italic>\n                    . The\n                    <jats:italic>Aedes aegypti<\/jats:italic>\n                    SCP\u2010x (AeSCP\u2010x) has 83% and 75% similarities to\n                    <jats:italic>Drosophila<\/jats:italic>\n                    and mammalian SCP\u2010x, respectively. However, the AeSCP\u2010x gene did not produce multiple transcripts, which is characteristic of the vertebrate SCP\u2010x gene. Levels of AeSCP\u2010x transcription were higher in larvae and pupae. Gut tissue showed the highest level of AeSCP\u2010x mRNA in larvae. In adults, low levels of AeSCP\u2010x transcription were detected in both sexes. Polyclonal antibodies against the sterol carrier protein\u20102 (SCP\u20102) domain of AeSCP\u2010x detected two proteins of 62\u00a0kDa and 13\u00a0kDa. The results indicate that AeSCP\u2010x is proteolytically cleaved after translation to produce a smaller protein that contains only the SCP\u20102 domain, which is similar to post\u2010translational modification of the vertebrate's SCP\u2010x to produce multiple products.\n                  <\/jats:p>","DOI":"10.1111\/j.0962-1075.2004.00510.x","type":"journal-article","created":{"date-parts":[[2004,9,16]],"date-time":"2004-09-16T11:09:44Z","timestamp":1095332984000},"page":"519-529","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Expression of a sterol carrier protein\u2010x gene in the Yellow fever mosquito,\n                    <i>Aedes aegypti<\/i>"],"prefix":"10.1111","volume":"13","author":[{"given":"Q.","family":"Lan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Wessely","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,9,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.41.26023"},{"key":"e_1_2_6_3_1","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/S0022-2275(20)32140-4","article-title":"Expression and intracellular processing of the 58 kDa sterol carrier protein\u20102\/3\u2010oxoacyl\u2010CoA thiolase in transfected mouse 1\u2010cell fibroblasts","volume":"40","author":"Atshaves B.P.","year":"1999","journal-title":"J Lipid Res"},{"key":"e_1_2_6_4_1","volume-title":"Current Protocols in Molecular Biology","author":"Ausubel F.M.","year":"1993"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.1996.67010046.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/arch.940050208"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1385\/CBB:32:1-3:291"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1997.t01-1-00252.x"},{"key":"e_1_2_6_9_1","volume-title":"Aedes aegypti (L.). 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