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Stent\u2010mounted valve prostheses have been successfully implanted in the pulmonic and aortic positions. These devices have been constructed using pericardial valve leaflets mounted inside balloon\u2010expandable or self\u2010expanding stents and have been used in patients who are high risk for valve replacement surgery. Percutaneous valve repair is also being developed for mitral regurgitation. Direct leaflet repair and percutaneous annuloplasty are being employed in clinical trials. All the percutaneous approaches are based on existing surgical techniques and offer less invasive alternatives. The era of percutaneous valve therapy has clearly arrived, and ongoing trials will define the clinical role for these new therapies.<\/jats:italic>\n          <\/jats:bold> <\/jats:p>","DOI":"10.1111\/j.1076-7460.2006.04880.x","type":"journal-article","created":{"date-parts":[[2007,1,26]],"date-time":"2007-01-26T20:03:42Z","timestamp":1169841822000},"page":"291-301","source":"Crossref","is-referenced-by-count":9,"title":["Percutaneous Treatment of Valvular Heart Disease: Catheter\u2010Based Aortic Valve Replacement and Mitral Valve Repair Therapies"],"prefix":"10.1111","volume":"15","author":[{"given":"Ted","family":"Feldman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard C.","family":"Herrmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred St.","family":"Goar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,26]]},"reference":[{"issue":"3","key":"e_1_2_5_2_2","first-page":"I49","article-title":"Octogenarians with aortic stenosis. 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