{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T04:52:44Z","timestamp":1758862364732},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,9,7]],"date-time":"2004-09-07T00:00:00Z","timestamp":1094515200000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Peripheral Nervous Sys"],"published-print":{"date-parts":[[2004,9]]},"abstract":"<jats:p><jats:bold>Abstract\u2003<\/jats:bold> Few reports exist on the association between the humoral immune response to glycolipids and neuropathic findings in diabetes. To address this issue, we assayed serum anti\u2010GM1, GD1b, GD1a, and sulfatides IgG and IgM in a group of 85 non\u2010selected diabetic patients, and correlated these antibodies to clinical and electrophysiological findings. Diabetic patients had higher mean titers of anti\u2010GM1 (IgM), GD1b, GD1a, and sulfatide (IgG) antibodies when compared to healthy controls. Patients with a positive titer of anti\u2010ganglioside antibodies had significant alterations of motor conduction parameters. The statistical significance increased when considering those patients with both anti\u2010ganglioside reactivity and a high value for glycosylated hemoglobin. Production of antibodies to ganglioside may follow the exposure of hidden motor nerve epitopes in damaged motor nerves and contribute to the neuropathy.<\/jats:p>","DOI":"10.1111\/j.1085-9489.2004.09303.x","type":"journal-article","created":{"date-parts":[[2004,9,7]],"date-time":"2004-09-07T15:48:38Z","timestamp":1094572118000},"page":"138-143","source":"Crossref","is-referenced-by-count":12,"title":["Motor nerve damage is associated with anti\u2010ganglioside antibodies in diabetes"],"prefix":"10.1111","volume":"9","author":[{"given":"Sabrina","family":"Mat\u00e0","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Betti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulio","family":"Masotti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Lolli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,9,7]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-1331.2003.00687.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9136(199706)14:6<461::AID-DIA380>3.0.CO;2-H"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03159953"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.6.799"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-5491.1999.00092.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.2337\/diacare.20.7.1183","volume":"20","author":"The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. 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