{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T13:30:42Z","timestamp":1698499842762},"reference-count":13,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,4,9]],"date-time":"2015-04-09T00:00:00Z","timestamp":1428537600000},"content-version":"vor","delay-in-days":8255,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[1992,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>DNA content and cell cycle distributions in paraffin\u2010embedded blocks of 19 skin biopsy specimens from 17 patients with chronic actinic dermatitis (CAD) [8 patients showed typical actinic reticuloid (AR)] were estimated by DNA cytometry. Sixty\u2010three percent (12\/19) of the skin specimens showed aneuploidy. In the 4 cases with the highest DNA indices (DI), ranging from 1.65 to 1.88 (mean: 1.84), the proportions of cells in S and G<jats:sub>2<\/jats:sub>\/M phases were increased, ranging from 15\u201348% (mean: 20%) and from 64\u201376% (mean: 70.5%), respectively. In 8 cases with DI ranging from 1.15\u20131.75 (mean: 1.5), the proportion of cells in S\u2010phase was also increased, ranging from 30\u201390% (mean: 81.1%). Histologically, it seems likely that the relatively high frequency of aneuploidy, DI, and proportions of cells in the S and\/or G<jats:sub>2<\/jats:sub>\/M phases were not proportional to epidermal or vascular endothelial hyperplasia, but they might be related to dermal lymphoid infiltration.<\/jats:p>","DOI":"10.1111\/j.1346-8138.1992.tb03726.x","type":"journal-article","created":{"date-parts":[[2015,4,10]],"date-time":"2015-04-10T22:32:09Z","timestamp":1428705129000},"page":"544-547","source":"Crossref","is-referenced-by-count":3,"title":["Aneuploidy in Chronic Actinic Dermatitis"],"prefix":"10.1111","volume":"19","author":[{"given":"Qiu","family":"Bingsen","sequence":"first","affiliation":[{"name":"Institute of Dermatology, Huashan Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liao","family":"Kanghuang","sequence":"additional","affiliation":[{"name":"Institute of Dermatology, Huashan Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ni","family":"Hongzhen","sequence":"additional","affiliation":[{"name":"Institute of Dermatology, Huashan Hospital"},{"name":"Unit of DNA flow cytometry Cancer Hospital, Shanghai Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,4,9]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1989.tb00909.x"},{"key":"e_1_2_2_3_1","unstructured":"QiuBS NiHZ:Application of DNA flow cytometry from paraffin\u2010embedded tissue to the discrimination of cutaneous malignant lymphoma from pseudolymphoma. 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