{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T20:47:12Z","timestamp":1791924432923,"version":"4.3.4"},"reference-count":7,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,4,9]],"date-time":"2015-04-09T00:00:00Z","timestamp":1428537600000},"content-version":"vor","delay-in-days":5517,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2000,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a 53\u2010year old man with symmetrical nonpitting edema, conjunctivitis, and acneiform eruptions on the face. Histopathological examination showed perifollicular lymphohistiocytic infiltration and telangiectasias in the upper dermis. Loosely aggregated non\u2010caseating granulomas were scattered through the dermis; some of them were seen in the perifollicular regions. The patient was treated with fleroxacin (100 mg\/day, orally) for two weeks with a marked reduction of both solid facial edema and periorbital edema.<\/jats:p>","DOI":"10.1111\/j.1346-8138.2000.tb02152.x","type":"journal-article","created":{"date-parts":[[2015,4,10]],"date-time":"2015-04-10T06:10:09Z","timestamp":1428646209000},"page":"214-216","source":"Crossref","is-referenced-by-count":17,"title":["Solid Facial Edema in a Patient with Rosacea"],"prefix":"10.1111","volume":"27","author":[{"given":"Hisashi","family":"Uhara","sequence":"first","affiliation":[{"name":"Department of Dermatology Shinshu University School of Medicine  Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeo","family":"Kawachi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Shinshu University School of Medicine  Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"Saida","sequence":"additional","affiliation":[{"name":"Department of Dermatology Shinshu University School of Medicine  Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,4,9]]},"reference":[{"key":"e_1_2_1_2_1","volume-title":"Dermatology in General Medicine","author":"Plewig G","year":"1993"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1001\/archderm.1995.01690210105020","article-title":"Persistent facial swelling in a patient with rosacea","volume":"131","author":"Scerri L","year":"1995","journal-title":"Arch Dermatol"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1992.tb00136.x"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1985.01660010091026"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1986.tb04533.x"},{"issue":"2","key":"e_1_2_1_7_1","first-page":"203","article-title":"General Pharmacological properties of fleroxacin","volume":"38","author":"Momo K","year":"1990","journal-title":"Chemotherapy"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1001\/archderm.1994.01690060078008","article-title":"Inhibition of a model of in vitro granuloma formation by tetracycline and ciprofroxacin: Involvement of protein kinase C","volume":"130","author":"Webster GF","year":"1994","journal-title":"Arch Dermatol"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1346-8138.2000.tb02152.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1346-8138.2000.tb02152.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T11:53:37Z","timestamp":1698580417000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1346-8138.2000.tb02152.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,3]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2000,3]]}},"alternative-id":["10.1111\/j.1346-8138.2000.tb02152.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1346-8138.2000.tb02152.x","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,3]]}}}