{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:46:20Z","timestamp":1762505180747},"reference-count":17,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2006,10,16]],"date-time":"2006-10-16T00:00:00Z","timestamp":1160956800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>We present further evidence that generalized morphea (GM) and primary biliary cirrhosis (PBC) may be associated. As far as we know, only six cases with this association have been previously reported in the published work, all of which were observed in women. We describe the case of a 62\u2010year\u2010old man diagnosed with M2\u2010antibody\u2010positive PBC who developed multiple generalized indurated plaques on the trunk and extremities 3\u00a0years later. Clinical history, laboratory data and histopathological examination were consistent with the diagnosis of GM. The coexistence in a male of these two entities that predominantly affect females reinforces the hypothesis that a pathogenic link exists between GM and PBC. Consequently, PBC should be looked for in all patients with GM.<\/jats:p>","DOI":"10.1111\/j.1346-8138.2006.00165.x","type":"journal-article","created":{"date-parts":[[2006,10,18]],"date-time":"2006-10-18T06:20:50Z","timestamp":1161152450000},"page":"709-713","source":"Crossref","is-referenced-by-count":11,"title":["Generalized morphea and primary biliary cirrhosis coexisting in a male patient"],"prefix":"10.1111","volume":"33","author":[{"given":"Marcos A.","family":"GONZ\u00c1LEZ\u2010L\u00d3PEZ","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"DRAKE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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Fernando","family":"VAL\u2010BERNAL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,16]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1999.tb03503.x"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001050050756"},{"key":"e_1_2_4_4_2","first-page":"199","article-title":"A case of primary biliary cirrhosis associated with generalized morphea","volume":"31","author":"Suyama Y","year":"1986","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1986.tb00465.x"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1992.tb00237.x"},{"key":"e_1_2_4_7_2","first-page":"300","article-title":"Koinzidenz von M2\u2010Antik\u00f6rper\u2010positiver prim\u00e4r bili\u00e4rer Zirrhose mit zirkumskripter Sclerodermie und erfolgreiche Therapie mit Ursodeoxychols\u00e4ure","volume":"21","author":"G\u00f6ring HD","year":"1995","journal-title":"Akt Dermatol"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2000.03732.x"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1053\/sder.2001.23093"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh487"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra043898"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(03)00270-8"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hch078"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13808-1"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2003.00780.x"},{"key":"e_1_2_4_16_2","first-page":"221","article-title":"Antimitochondrial antibodies in patients with chronic graft versus\u2010host disease","volume":"10","author":"Siegert W","year":"1992","journal-title":"Bone Marrow Transplant"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.1996.d01-756.x"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118851"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1346-8138.2006.00165.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1346-8138.2006.00165.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T07:05:11Z","timestamp":1697180711000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1346-8138.2006.00165.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10]]},"references-count":17,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["10.1111\/j.1346-8138.2006.00165.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1346-8138.2006.00165.x","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10]]}}}