{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:45:35Z","timestamp":1759333535916},"reference-count":18,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2006,11,28]],"date-time":"2006-11-28T00:00:00Z","timestamp":1164672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Discoid lupus erythematosus (DLE), a cutaneous form of lupus erythematosus, is characterized as atrophic and scaly erythema and the lesions are often refractory to a wide range of topical or systemic therapies. Herein, we present four cases of DLE that were successfully treated with topical tacrolimus. Tacrolimus ointment (0.1%) was applied to DLE lesions twice daily and the erythematous plaques readily diminished after 4\u20138 weeks. Adverse effects, such as burning sensation or irritations, were not observed. These results indicate that topical tacrolimus might be an effective and alternative treatment to control DLE.<\/jats:p>","DOI":"10.1111\/j.1346-8138.2006.00203.x","type":"journal-article","created":{"date-parts":[[2006,11,28]],"date-time":"2006-11-28T13:12:29Z","timestamp":1164719549000},"page":"887-891","source":"Crossref","is-referenced-by-count":19,"title":["Successful treatment with topical tacrolimus in four cases of discoid lupus erythematosus"],"prefix":"10.1111","volume":"33","author":[{"given":"Masayoshi","family":"SUGANO","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoichi","family":"SHINTANI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"KOBAYASHI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriyuki","family":"SAKAKIBARA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iwao","family":"ISOMURA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akimichi","family":"MORITA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,11,28]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200304070-00002"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2004.05782.x"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70541-9"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1159\/000065843"},{"key":"e_1_2_4_6_2","first-page":"451","article-title":"Topical tacrolimus is effective for facial lesions of psoriasis","volume":"80","author":"Yamamoto T","year":"2000","journal-title":"Acta Derma Venereol"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2003.tb00482.x"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.124703"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.40.1256"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(96)80599-8"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/095466301750163518"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2005.tb00745.x"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05186.x"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1986.tb05720.x"},{"key":"e_1_2_4_15_2","doi-asserted-by":"crossref","unstructured":"JessopS WhitelawD JordaanF.Drugs for discoid lupus erythematosus.Cochrane Database Syst Rev2001; CD002954.","DOI":"10.1002\/14651858.CD002954"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.488616.x"},{"key":"e_1_2_4_17_2","first-page":"50","article-title":"Topical FK506 (tacrolimus) therapy for facial erythematosus lesion of cutaneous lupus erythematosus and dermatomyositis","volume":"12","author":"Yoshimasu T","year":"2002","journal-title":"Eur J Dermatol"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh325"},{"key":"e_1_2_4_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.9.1170"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1346-8138.2006.00203.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1346-8138.2006.00203.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T07:10:54Z","timestamp":1697181054000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1346-8138.2006.00203.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,11,28]]},"references-count":18,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["10.1111\/j.1346-8138.2006.00203.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1346-8138.2006.00203.x","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,11,28]]}}}