{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T17:27:56Z","timestamp":1767374876988},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2008,8,6]],"date-time":"2008-08-06T00:00:00Z","timestamp":1217980800000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Cutaneous and systemic plasmacytosis (CSP) is an exceedingly rare condition arising primarily in patients of Japanese descent. Herein, we describe a patient of mainland Chinese origin suffering CSP. A 49\u2010year\u2010old Chinese male had asymptomatic brownish\u2010red plaques and papules of the face and trunk for 6\u00a0years. Physical examination revealed innumerable symmetric red\u2010brownish macules on face and trunk with fewer red\u2010brownish papules scattered among the macules. Chemical analysis revealed hypergammaglobulinemia. Computerized tomography scan discovered some lymphadenopathy in the axillary, paratracheal and pulmonary regions. Histological examination showed focal perivascular and periadnexal infiltrate of mainly plasma cells in the superficial and deep dermis. Immunohistochemical study showed that a great number of the infiltrating cells were CD20\u2010positive. The infiltrated polyclonal plasma cells expressed both \u03ba and \u03bb light chains. Topical therapy with tacrolimus 0.1% ointment for 2\u00a0months reduced the thickness and pigmentation of the facial skin lesions. The lesions resumed the original appearance 3\u00a0weeks after discontinuing the therapy. To the best of our knowledge, this is the first case of CSP from mainland China.<\/jats:p>","DOI":"10.1111\/j.1346-8138.2008.00516.x","type":"journal-article","created":{"date-parts":[[2008,8,7]],"date-time":"2008-08-07T02:01:25Z","timestamp":1218074485000},"page":"536-540","source":"Crossref","is-referenced-by-count":17,"title":["Cutaneous and systemic plasmacytosis: A Chinese case"],"prefix":"10.1111","volume":"35","author":[{"given":"Hui\u2010Jun","family":"MA","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"LIU","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"You","family":"LI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guang","family":"ZHAO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ru\u2010Song","family":"MENG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong\u2010Guang","family":"LI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,8,6]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2002.00411.x"},{"key":"e_1_2_4_3_2","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1001\/archderm.1986.01660230106022","article-title":"Systemic plasmacytosis. 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