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The pathogenesis of metabolic syndrome is supposed to be related to increased levels of adipocytokines, such as tumor necrosis factor\u2010\u03b1 (TNF\u2010\u03b1) and adiponectin. Recent study has revealed a high prevalence of metabolic syndrome in psoriatics compared with other skin diseases. Biologic agents, including anti\u2010TNF\u2010\u03b1 antibodies, are recommended as the first\u2010line treatment for psoriatics with metabolic syndrome. 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