{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T21:42:52Z","timestamp":1748554972594},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,3,2]],"date-time":"2012-03-02T00:00:00Z","timestamp":1330646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Individuals with a personal history of non\u2010melanoma skin cancer (NMSC) are known to have an increased risk of subsequent cancers. However, most of the studies regarding this fact were done on Caucasian populations. We investigated whether Korean patients with NMSC have an increased risk of developing second cancers compared to the general Korean population. Five hundred and thirty\u2010two patients diagnosed with NMSC at the Department of Dermatology of Yonsei University Health System from 1999 to 2008 were assessed for development of second cancers. The overall second cancer incidence was increased among patients diagnosed with NMSC compared with the general population in Korea: 37 second cancer total (standardized incidence ratio [SIR] 1.38, 95% confidence interval [CI] 1.10\u20131.90); 23 second cancers in males (SIR 4.24, 95% CI 2.69\u20136.36); and 14 second cancers in females (SIR 2.28, 95% CI 1.25\u20133.83). There were significantly increased incidence ratios for NMSC (eight second cancers [SIR 9.52, 95% CI 4.11\u201318.77]), bladder cancer (four second cancers [SIR 4.21, 95% CI 1.15\u201310.78]) and nasopharyngeal cancer (one second cancer [SIR 20.00, 95% CI: 1.51\u201325.33]). Korean patients diagnosed with NMSC had more second cancers, particularly other skin cancers. This study provides additional evidence that NMSC may be a clinically significant and substantial risk factor for second cancers even in a Korean population, in which the incidence of NMSC is much lower than Caucasians.<\/jats:p>","DOI":"10.1111\/j.1346-8138.2011.01495.x","type":"journal-article","created":{"date-parts":[[2012,3,4]],"date-time":"2012-03-04T15:03:25Z","timestamp":1330873405000},"page":"541-544","source":"Crossref","is-referenced-by-count":8,"title":["Risk of second cancers after the diagnosis of non\u2010melanoma skin cancer in Korean patients"],"prefix":"10.1111","volume":"39","author":[{"given":"Mi Ryung","family":"ROH","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Joon","family":"SHIN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo Hyun","family":"LEE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kee Yang","family":"CHUNG","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3,2]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05223.x"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.08.063"},{"key":"e_1_2_5_4_2","first-page":"762","article-title":"A clinicopathological study of basal cell carcinoma in Korean patients","volume":"38","author":"Song ES","year":"2000","journal-title":"Korean J Dermatol"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/PL00012091"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1995.01690140048007"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djn260"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.12.1524"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2004.00893.x"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1992.03480240067036"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(20000301)85:5<639::AID-IJC7>3.0.CO;2-L"},{"key":"e_1_2_5_12_2","volume-title":"Annual Report of the Korea Central Cancer Registry","author":"Ministry of Health and Welfare","year":"2008"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19990209)80:4<511::AID-IJC5>3.0.CO;2-P"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0215(20000715)87:2<283::AID-IJC21>3.0.CO;2-I"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6604842"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-125-10-199611150-00005"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.5.647"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.03.031"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12399400"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.74.4.1688"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/59.4.1227"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgi123"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1346-8138.2011.01495.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1346-8138.2011.01495.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T13:56:01Z","timestamp":1698674161000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1346-8138.2011.01495.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,2]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.1111\/j.1346-8138.2011.01495.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1346-8138.2011.01495.x","archive":["Portico"],"relation":{},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,2]]}}}