{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T02:47:23Z","timestamp":1785293243537,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2012,7,11]],"date-time":"2012-07-11T00:00:00Z","timestamp":1341964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Dermatology"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Over several decades, topical and systemic antibiotics have been the mainstay of treatment for acne vulgaris. The widespread and long\u2010term use of antibiotics in the treatment of acne has resulted in the spread of resistant bacterial strains and treatment failure. We aimed to examine the bacteriology of acne vulgaris and to evaluate its susceptibility to the antibiotics widely used for acne in Korea. We examined the species of bacteria aerobically and anaerobically isolated from 100 Korean acne patients. Among the bacteria isolated,\n                    <jats:italic>Staphylococcus epidermidis<\/jats:italic>\n                    (36 patients) was the most common, followed by\n                    <jats:italic>Propionibacterium acnes<\/jats:italic>\n                    (30 patients). Eleven strains of\n                    <jats:italic>P.\u00a0acnes<\/jats:italic>\n                    (36.7%) and 25 strains of\n                    <jats:italic>S.\u00a0epidermidis<\/jats:italic>\n                    (69.4%) were resistant to one or other of the antibiotics tested. A higher proportion of\n                    <jats:italic>P.\u00a0acnes<\/jats:italic>\n                    isolates were resistant to clindamycin (30%) and erythromycin (26.7%), than to any other antibiotics tested (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003=\u20030.0003). Some\n                    <jats:italic>S.\u00a0epidermidis<\/jats:italic>\n                    isolates were resistant to tetracycline and doxycycline in addition to clindamycin and erythromycin. In the previous studies, few strains of\n                    <jats:italic>P.\u00a0acnes<\/jats:italic>\n                    were found to be resistant to any of the antibiotics, but this study shows that antibiotic\u2010resistant strains have been increasing in Korea acne patients.\n                  <\/jats:p>","DOI":"10.1111\/j.1346-8138.2012.01626.x","type":"journal-article","created":{"date-parts":[[2012,7,11]],"date-time":"2012-07-11T07:10:03Z","timestamp":1341990603000},"page":"833-837","source":"Crossref","is-referenced-by-count":63,"title":["Antibiotic resistance of microbial strains isolated from Korean acne patients"],"prefix":"10.1111","volume":"39","author":[{"given":"Sang Ho","family":"MOON","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Soo","family":"ROH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Hoon","family":"KIM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong Eun","family":"KIM","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joo Yeon","family":"KO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Suck","family":"RO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,7,11]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0906-6705.2005.0285a.x"},{"key":"e_1_2_6_3_2","first-page":"1","article-title":"Pathogenesis of acne: research advances","volume":"19","author":"Harper JC","year":"2003","journal-title":"Adv Dermatol"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.01.019"},{"key":"e_1_2_6_5_2","first-page":"593","article-title":"Antibiotics resistance rate","volume":"17","author":"Leyden JJ","year":"1976","journal-title":"Cutis"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(83)70005-8"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-16-3-271"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1988.tb03667.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000067822"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.03956.x"},{"key":"e_1_2_6_11_2","first-page":"1241","article-title":"Korean Acne Grading System","volume":"42","author":"Sung KJ","year":"2004","journal-title":"Korean J Dermatol"},{"key":"e_1_2_6_12_2","unstructured":"Clinical and Laboratory Standards Institute (CLSI).Performance standards for antimicrobial susceptibility testing; thirteen informational supplement. CLSI Document M100\u2010S13. Wayne PA:CLSI 2003."},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10375.x"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05067.x"},{"key":"e_1_2_6_15_2","first-page":"22","article-title":"Antibiotic sensitivity of Propionibacterium acnes isolates from patients with acne vulgaris in a tertiary dermatological referral centre in Singapore","volume":"30","author":"Tan HH","year":"2001","journal-title":"Ann Acad Med Singapore"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.2008.00081.x"},{"key":"e_1_2_6_17_2","first-page":"437","article-title":"A Study on the MIC of Antibiotics for Propionibacterium acnes in patients with acne","volume":"33","author":"Lim YS","year":"1995","journal-title":"Korean J Dermatol"},{"key":"e_1_2_6_18_2","first-page":"871","article-title":"Microorganisms isolated from acne and their antibiotic susceptibility","volume":"43","author":"Ki HG","year":"2005","journal-title":"Korean J Dermatol"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2010.01109.x"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anaerobe.2006.06.001"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1142\/S0192415X05002783"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.2323\/jgam.54.101"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1993.tb00235.x"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1994.tb01715.x"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1159\/000424238"}],"container-title":["The Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1346-8138.2012.01626.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1346-8138.2012.01626.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T05:02:02Z","timestamp":1698642122000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1346-8138.2012.01626.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,11]]},"references-count":24,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["10.1111\/j.1346-8138.2012.01626.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1346-8138.2012.01626.x","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717950458.793455710","asserted-by":"object"}]},"ISSN":["0385-2407","1346-8138"],"issn-type":[{"value":"0385-2407","type":"print"},{"value":"1346-8138","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,11]]}}}