{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T14:03:15Z","timestamp":1784037795994,"version":"3.55.0"},"reference-count":159,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,2,27]],"date-time":"2006-02-27T00:00:00Z","timestamp":1140998400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:bold>Background\u2003<\/jats:bold> The popular dance drug ecstasy (3,4\u2010methylenedioxymethamphetamine: MDMA and some analogues) causes selective and persistent neurotoxic damage of central serotonergic neurones in laboratory animals. Serotonin plays a role in numerous functional systems in the central nervous system (CNS). Consequently, various abnormalities including psychiatric, vegetative, neuroendocrine and cognitive disorders could be expected in humans following MDMA\u2010induced neurotoxic brain damage.<\/jats:p><jats:p><jats:bold>Aims\u2003<\/jats:bold> In recent years, the question of ecstasy\u2010induced neurotoxicity and possible functional sequelae has been addressed in several studies with drug users. The aim of this paper was to review this literature and weigh the strength of the evidence for persistent brain damage in ecstasy users.<\/jats:p><jats:p><jats:bold>Methods\u2003<\/jats:bold> We used Medline to view all available publications on \u2018ecstasy\u2019 or \u2018MDMA\u2019. All available studies dealing with ecstasy users entered this analysis.<\/jats:p><jats:p><jats:bold>Findings and conclusions\u2003<\/jats:bold> Despite large methodological problems the bulk of evidence suggests residual alterations of serotonergic transmission in MDMA users, although at least partial restitution may occur after long\u2010term abstinence. However, functional sequelae may persist even after longer periods of abstinence. To date, the most consistent findings associate subtle cognitive, particularly memory, impairments with heavy ecstasy use. However, the evidence cannot be considered definite and the issues of possible pre\u2010existing traits or the effects of polydrug use are not resolved.<\/jats:p><jats:p><jats:bold>Recommendations\u2003<\/jats:bold> Questions about the neurotoxic effects of ecstasy on the brain remain highly topical in light of its popularity among young people. More longitudinal and prospective studies are clearly needed in order to obtain a better understanding of the possible long\u2010term sequelae of ecstasy use in humans.<\/jats:p>","DOI":"10.1111\/j.1360-0443.2006.01314.x","type":"journal-article","created":{"date-parts":[[2006,2,27]],"date-time":"2006-02-27T08:36:48Z","timestamp":1141029408000},"page":"348-361","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":123,"title":["Neurotoxicity of methylenedioxyamphetamines (MDMA; ecstasy) in humans: how strong is the evidence for persistent brain damage?"],"prefix":"10.1111","volume":"101","author":[{"given":"E.","family":"Gouzoulis\u2010Mayfrank","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Daumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,2,27]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1054-139X(01)00315-9"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1124\/pr.55.3.3"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0376-8716(01)00195-8"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1159\/000018925"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000050709"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.2190\/RJX5-WRA6-BNG5-Q2TY"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-003-1712-7"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1080\/02791072.1986.10472362"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/429126a"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1993.01820130081018"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130050860"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2004.08.007"},{"key":"e_1_2_5_14_2","first-page":"616","article-title":"Lasting effects of 3,4\u2010methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations","volume":"261","author":"Ricaurte GA","year":"1992","journal-title":"J Pharmacol Exp Ther"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4274(99)00216-7"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1992.72.1.165"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3908(98)00029-X"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.15-08-05476.1995"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.19-12-05096.1999"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(98)00139-5"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-185X.1997.tb00010.x"},{"key":"e_1_2_5_22_2","first-page":"529","article-title":"Behavioral and neurochemical effects of orally administered MDMA in the rodent and nonhuman primate","volume":"10","author":"Slikker WJr","year":"1989","journal-title":"Neurotoxicology"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0149-7634(95)00064-X"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(02)00380-9"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130050978"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(01)01512-6"},{"key":"e_1_2_5_27_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-09-03228.2001"},{"key":"e_1_2_5_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-3057(03)00217-X"},{"key":"e_1_2_5_29_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-003-1452-8"},{"key":"e_1_2_5_30_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1300185"},{"key":"e_1_2_5_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9384(03)00092-1"},{"key":"e_1_2_5_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(00)00185-8"},{"key":"e_1_2_5_33_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-001-0942-9"},{"key":"e_1_2_5_34_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008877-200305000-00003"},{"key":"e_1_2_5_35_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130100900"},{"key":"e_1_2_5_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(02)01820-4"},{"key":"e_1_2_5_37_2","doi-asserted-by":"publisher","DOI":"10.1136\/emj.16.3.194"},{"key":"e_1_2_5_38_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1360-0443.2002.00222.x"},{"key":"e_1_2_5_39_2","first-page":"1","article-title":"Pharmacokinetic profile of single and repeated oral doses of MDMA in squirrel monkeys: relationship to lasting effecs on brain serotonin neurons","volume":"26","author":"Mechan A","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"e_1_2_5_40_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1300442"},{"key":"e_1_2_5_41_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001150050544"},{"key":"e_1_2_5_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0701859"},{"key":"e_1_2_5_43_2","doi-asserted-by":"publisher","DOI":"10.1159\/000080961"},{"key":"e_1_2_5_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0082(96)00033-0"},{"key":"e_1_2_5_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(99)00022-6"},{"key":"e_1_2_5_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(99)00045-7"},{"key":"e_1_2_5_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4927(99)00048-7"},{"key":"e_1_2_5_48_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004714-200102000-00012"},{"key":"e_1_2_5_49_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2202001602"},{"key":"e_1_2_5_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-977X(99)80198-9"},{"key":"e_1_2_5_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2003.07.001"},{"key":"e_1_2_5_52_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2586(199910)10:4<521::AID-JMRI4>3.0.CO;2-9"},{"key":"e_1_2_5_53_2","first-page":"231","article-title":"Reduced N\u2010acetylaspartate levels in the frontal cortex of 3,4\u2010methylenedioxymethamphetamine (Ecstasy) users: preliminary results","volume":"23","author":"Reneman L","year":"2002","journal-title":"AJNR"},{"key":"e_1_2_5_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2004.03.004"},{"key":"e_1_2_5_55_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006231-200108000-00007"},{"key":"e_1_2_5_56_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130051035"},{"key":"e_1_2_5_57_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200001170-00031"},{"key":"e_1_2_5_58_2","first-page":"125","article-title":"Monoamine metabolites in the cerebrospinal fluid of recreational users of 3,4\u2010methylenediethyloxymethamphetamine (MDMA); \u2018ecstasy\u2019)","volume":"8","author":"Peroutka SJ","year":"1987","journal-title":"Res Commun Subst Abuse"},{"key":"e_1_2_5_59_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1990.tb16919.x"},{"key":"e_1_2_5_60_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.6.1532"},{"key":"e_1_2_5_61_2","doi-asserted-by":"publisher","DOI":"10.1038\/npp.1994.15"},{"key":"e_1_2_5_62_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130050967"},{"key":"e_1_2_5_63_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)04329-3"},{"key":"e_1_2_5_64_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.175.1.63"},{"key":"e_1_2_5_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-3057(01)00708-0"},{"key":"e_1_2_5_66_2","doi-asserted-by":"publisher","DOI":"10.1002\/syn.10130"},{"key":"e_1_2_5_67_2","first-page":"678","article-title":"Comparison of (+)\u2010(11) C\u2010McN5652 (11) C\u2010DASB as serotonin transporter radioligands under various experimental conditions","volume":"43","author":"Szabo Z","year":"2002","journal-title":"J Nucleic Med"},{"key":"e_1_2_5_68_2","doi-asserted-by":"crossref","unstructured":"McCannUD SzaboZ SeckinE RosenblattP MathewsWB RavertHT et al.Quantitative PET studies of the serotonin transporter in MDMA users and controls using [(11)C]McN5652 and [(11)C]DASB.Neuropsychopharmacology2005[Advance online publication 20 April].","DOI":"10.1038\/sj.npp.1300736"},{"key":"e_1_2_5_69_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-002-1383-9"},{"key":"e_1_2_5_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)06888-X"},{"key":"e_1_2_5_71_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.58.10.901"},{"key":"e_1_2_5_72_2","first-page":"375","article-title":"Long\u2010term effects of \u2018ecstasy\u2019 use on serotonin transporters of the brain investigated by PET","volume":"44","author":"Buchert R","year":"2003","journal-title":"J Nucleic Med"},{"key":"e_1_2_5_73_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.161.7.1181"},{"key":"e_1_2_5_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(01)00366-9"},{"key":"e_1_2_5_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3908(92)90126-A"},{"key":"e_1_2_5_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-7634(98)00046-3"},{"key":"e_1_2_5_77_2","doi-asserted-by":"publisher","DOI":"10.1159\/000026667"},{"key":"e_1_2_5_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0376-8716(98)00051-9"},{"key":"e_1_2_5_79_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0376-8716(99)00002-2"},{"key":"e_1_2_5_80_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0376-8716(02)00190-4"},{"key":"e_1_2_5_81_2","doi-asserted-by":"publisher","DOI":"10.1159\/000026665"},{"key":"e_1_2_5_82_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(98)00012-8"},{"key":"e_1_2_5_83_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0376-8716(00)80013-7"},{"key":"e_1_2_5_84_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004850-199801000-00001"},{"key":"e_1_2_5_85_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(99)00180-8"},{"key":"e_1_2_5_86_2","doi-asserted-by":"publisher","DOI":"10.1002\/hup.342"},{"key":"e_1_2_5_87_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130000563"},{"key":"e_1_2_5_88_2","doi-asserted-by":"publisher","DOI":"10.1177\/026988110101500310"},{"key":"e_1_2_5_89_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-004-1791-0"},{"key":"e_1_2_5_90_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130100907"},{"key":"e_1_2_5_91_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-003-1719-0"},{"key":"e_1_2_5_92_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130100897"},{"key":"e_1_2_5_93_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-003-1705-6"},{"key":"e_1_2_5_94_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-003-1723-4"},{"key":"e_1_2_5_95_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.162.3.609"},{"key":"e_1_2_5_96_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-4328(03)00220-1"},{"key":"e_1_2_5_97_2","first-page":"S24","article-title":"Sleep and serotonin: an unfinished story","volume":"21","author":"Jouvet M.","year":"1999","journal-title":"Neuropsychopharmacology"},{"key":"e_1_2_5_98_2","doi-asserted-by":"publisher","DOI":"10.1016\/0278-5846(95)00231-6"},{"key":"e_1_2_5_99_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/16.6.560"},{"key":"e_1_2_5_100_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(98)00018-3"},{"key":"e_1_2_5_101_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1781(00)00114-1"},{"key":"e_1_2_5_102_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002139900361"},{"key":"e_1_2_5_103_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1989.01810010022003"},{"key":"e_1_2_5_104_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130051142"},{"key":"e_1_2_5_105_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(01)01306-3"},{"key":"e_1_2_5_106_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-8760(92)90059-K"},{"key":"e_1_2_5_107_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3223(93)90137-3"},{"key":"e_1_2_5_108_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3223(94)00118-M"},{"key":"e_1_2_5_109_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(99)00140-2"},{"key":"e_1_2_5_110_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.10.1687"},{"key":"e_1_2_5_111_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130100811"},{"key":"e_1_2_5_112_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1300396"},{"key":"e_1_2_5_113_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-003-1729-y"},{"key":"e_1_2_5_114_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-7634(99)00067-6"},{"key":"e_1_2_5_115_2","doi-asserted-by":"publisher","DOI":"10.3109\/07853890008998828"},{"key":"e_1_2_5_116_2","first-page":"1292","article-title":"Executive function in abstinent MDMA (\u2018ecstasy\u2019) users","volume":"7","author":"Zakzanis KK","year":"2001","journal-title":"Med Sci Monit"},{"key":"e_1_2_5_117_2","doi-asserted-by":"publisher","DOI":"10.1177\/026988110101500406"},{"key":"e_1_2_5_118_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2004.02.008"},{"key":"e_1_2_5_119_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-004-1832-8"},{"key":"e_1_2_5_120_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.68.6.719"},{"key":"e_1_2_5_121_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5846(03)00114-3"},{"key":"e_1_2_5_122_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-002-1071-9"},{"key":"e_1_2_5_123_2","doi-asserted-by":"publisher","DOI":"10.1348\/0007126042369785"},{"key":"e_1_2_5_124_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.1997.tb02951.x"},{"key":"e_1_2_5_125_2","doi-asserted-by":"publisher","DOI":"10.1348\/000712600161772"},{"key":"e_1_2_5_126_2","doi-asserted-by":"publisher","DOI":"10.1002\/hup.586"},{"key":"e_1_2_5_127_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-003-1755-9"},{"key":"e_1_2_5_128_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-004-2083-4"},{"key":"e_1_2_5_129_2","doi-asserted-by":"publisher","DOI":"10.1002\/hup.670"},{"key":"e_1_2_5_130_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66942-5"},{"key":"e_1_2_5_131_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291701003828"},{"key":"e_1_2_5_132_2","doi-asserted-by":"publisher","DOI":"10.3109\/00952999209026070"},{"key":"e_1_2_5_133_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130050714"},{"key":"e_1_2_5_134_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130050803"},{"key":"e_1_2_5_135_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130050057"},{"key":"e_1_2_5_136_2","doi-asserted-by":"publisher","DOI":"10.1177\/0269881103174016"},{"key":"e_1_2_5_137_2","doi-asserted-by":"publisher","DOI":"10.1076\/clin.17.4.446.27939"},{"key":"e_1_2_5_138_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291703001132"},{"key":"e_1_2_5_139_2","doi-asserted-by":"crossref","unstructured":"MontgomeryC FiskJE NewcombeR.The nature of ecstasy\u2010group related deficits in associative learning.Psychopharmacology2005[Epub ahead of print 25 January].","DOI":"10.1007\/s00213-004-2131-0"},{"key":"e_1_2_5_140_2","doi-asserted-by":"publisher","DOI":"10.1159\/000026666"},{"key":"e_1_2_5_141_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130000591"},{"key":"e_1_2_5_142_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1360-0443.2002.00213.x"},{"key":"e_1_2_5_143_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-003-1561-4"},{"key":"e_1_2_5_144_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002130000467"},{"key":"e_1_2_5_145_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.62.4.418-a"},{"key":"e_1_2_5_146_2","doi-asserted-by":"publisher","DOI":"10.2466\/PR0.95.5.192-196"},{"key":"e_1_2_5_147_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(01)01177-5"},{"key":"e_1_2_5_148_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-003-1463-5"},{"key":"e_1_2_5_149_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.7.966"},{"key":"e_1_2_5_150_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2004.12.002"},{"key":"e_1_2_5_151_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0926-6410(03)00075-2"},{"key":"e_1_2_5_152_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-004-1908-5"},{"key":"e_1_2_5_153_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200310270-00021"},{"key":"e_1_2_5_154_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2004.06.011"},{"key":"e_1_2_5_155_2","doi-asserted-by":"crossref","unstructured":"DaumannJ FischermannT HeekerenK HenkeK ThronA Gouzoulis\u2010MayfrankE.Memory\u2010related hippocampal dysfunction in poly\u2010drug ecstasy (3 4\u2010methylenedioxymethamphetamine) users.Psychopharmacology2004[Epub ahead of print 15 September].","DOI":"10.1007\/s00213-004-2002-8"},{"key":"e_1_2_5_156_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-003-1679-4"},{"key":"e_1_2_5_157_2","doi-asserted-by":"publisher","DOI":"10.1177\/026988119801200110"},{"key":"e_1_2_5_158_2","doi-asserted-by":"publisher","DOI":"10.1159\/000026666"},{"key":"e_1_2_5_159_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0379-0738(97)00123-0"},{"key":"e_1_2_5_160_2","doi-asserted-by":"publisher","DOI":"10.1520\/JFS14694J"}],"container-title":["Addiction"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1360-0443.2006.01314.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1360-0443.2006.01314.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T21:07:29Z","timestamp":1697576849000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1360-0443.2006.01314.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2,27]]},"references-count":159,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2006,3]]}},"alternative-id":["10.1111\/j.1360-0443.2006.01314.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1360-0443.2006.01314.x","archive":["Portico"],"relation":{},"ISSN":["0965-2140","1360-0443"],"issn-type":[{"value":"0965-2140","type":"print"},{"value":"1360-0443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2,27]]},"assertion":[{"value":"2006-02-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}