{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:25:32Z","timestamp":1792002332820,"version":"4.4.0"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2009,2,10]],"date-time":"2009-02-10T00:00:00Z","timestamp":1234224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2009,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>It has been claimed that mothers' drinking during pregnancy may affect the neurodevelopment of around 1% of all children. If this is true, then prenatal alcohol exposure represents an important risk factor for neurodevelopmental problems, giving rise to a large burden of disability which could be potentially preventable. Evidence to support this idea has come from animal experiments and human observational studies. However, such findings need to be supported by more robust research designs. Because randomized controlled trials in this area are neither feasible nor ethical, suggestions are made for further research making more use of natural experiments.<\/jats:p>","DOI":"10.1111\/j.1360-0443.2008.02441.x","type":"journal-article","created":{"date-parts":[[2009,2,10]],"date-time":"2009-02-10T15:32:13Z","timestamp":1234279933000},"page":"1270-1273","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":71,"title":["Alcohol consumption during pregnancy and its effects on neurodevelopment: what is known and what remains uncertain"],"prefix":"10.1111","volume":"104","author":[{"given":"Ron","family":"Gray","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raja A. S.","family":"Mukherjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Rutter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,7,13]]},"reference":[{"key":"e_1_2_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)91092-1"},{"key":"e_1_2_3_3_2","first-page":"476","article-title":"Children of alcoholic parents: abnormalities observed in 127 cases","volume":"8","author":"Lemoine P.","year":"1968","journal-title":"Ouest Med"},{"key":"e_1_2_3_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/15353702-0323006-03"},{"key":"e_1_2_3_5_2","unstructured":"Surgeon General.U.S. Surgeon General Releases Advisory on Alcohol Use in Pregnancy: Urges Women Who are Pregnant or Who May Become Pregnant to Abstain from Alcohol.2005. Available at:http:\/\/www.surgeongeneral.gov\/pressreleases\/sg02222005.html(accessed 1 June 2008)."},{"key":"e_1_2_3_6_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2007.tb00999.x"},{"key":"e_1_2_3_7_2","first-page":"159","article-title":"Estimating the prevalence of fetal alcohol syndrome. A summary","volume":"25","author":"May P. A.","year":"2001","journal-title":"Alcohol Res Health"},{"key":"e_1_2_3_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2007.120220"},{"key":"e_1_2_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2006.11.007"},{"key":"e_1_2_3_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2006.00188.x"},{"key":"e_1_2_3_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/15353702-0323006-06"},{"key":"e_1_2_3_12_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5455.1056"},{"key":"e_1_2_3_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-8624.1997.tb01959.x"},{"key":"e_1_2_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-5217-5"},{"key":"e_1_2_3_15_2","first-page":"282","article-title":"Effects of prenatal alcohol exposure on child development","volume":"26","author":"Jacobson J. L.","year":"2002","journal-title":"Alcohol Res Health"},{"key":"e_1_2_3_16_2","volume-title":"Review of the Fetal Effects of Prenatal Alcohol Exposure. Report to the Department of Health","author":"Gray R.","year":"2006"},{"key":"e_1_2_3_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/17.4.950"},{"key":"e_1_2_3_18_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.325.7378.1437"},{"key":"e_1_2_3_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9926(199711)56:5<317::AID-TERA5>3.0.CO;2-U"},{"key":"e_1_2_3_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.1998.tb03651.x"},{"key":"e_1_2_3_21_2","volume-title":"Fetal Alcohol Spectrum Disorders: A Guide for Healthcare Professionals","author":"British Medical Association Board of Science","year":"2007"},{"key":"e_1_2_3_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-6916.2007.00050.x"},{"key":"e_1_2_3_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.64.11.1296"},{"key":"e_1_2_3_24_2","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e318187cc31"},{"key":"e_1_2_3_25_2","first-page":"A22","article-title":"The effect of reduction in the price of alcohol on socioeconomic differences in alcohol\u2010related mortality: a natural experiment based on register data","volume":"61","author":"Herttua K.","year":"2007","journal-title":"J Epidemiol Community Health"},{"key":"e_1_2_3_26_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.330.7499.1076"},{"key":"e_1_2_3_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.02.028"}],"container-title":["Addiction"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1360-0443.2008.02441.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1360-0443.2008.02441.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T07:06:38Z","timestamp":1698735998000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1360-0443.2008.02441.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7,13]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2009,8]]}},"alternative-id":["10.1111\/j.1360-0443.2008.02441.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1360-0443.2008.02441.x","archive":["Portico"],"relation":{},"ISSN":["0965-2140","1360-0443"],"issn-type":[{"value":"0965-2140","type":"print"},{"value":"1360-0443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7,13]]},"assertion":[{"value":"2009-07-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}