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Lower maternal weight at delivery, later estimated gestational age (<jats:styled-content style=\"fixed-case\">EGA<\/jats:styled-content>), maternal use of selective serotonin re\u2010uptake inhibitors (<jats:styled-content style=\"fixed-case\">SSRI<\/jats:styled-content>s), vaginal delivery and higher infant birthweight predicted higher peak <jats:styled-content style=\"fixed-case\">NAS<\/jats:styled-content> scores. Higher infant birthweight and greater maternal nicotine use at delivery predicted receipt of <jats:styled-content style=\"fixed-case\">NAS<\/jats:styled-content> treatment for infants. Maternal use of <jats:styled-content style=\"fixed-case\">SSRI<\/jats:styled-content>s, higher nicotine use and fewer days of study medication received also predicted total dose of medication required to treat <jats:styled-content style=\"fixed-case\">NAS<\/jats:styled-content> symptoms. No variables predicted length of treatment for <jats:styled-content style=\"fixed-case\">NAS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Maternal weight at delivery, estimated gestational age, infant birthweight, delivery type, maternal nicotine use and days of maternal study medication received and the use of psychotropic medications in pregnancy may play a role in the expression of neonatal abstinence syndrome severity in infants exposed to either methadone or buprenorphine.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1360-0443.2012.04038.x","type":"journal-article","created":{"date-parts":[[2012,10,29]],"date-time":"2012-10-29T16:30:49Z","timestamp":1351528249000},"page":"45-52","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":92,"title":["Predicting treatment for neonatal abstinence syndrome in infants born to women maintained on opioid agonist medication"],"prefix":"10.1111","volume":"107","author":[{"given":"Karol","family":"Kaltenbach","sequence":"first","affiliation":[{"name":"Department of Pediatrics Jefferson Medical College Thomas Jefferson University  Philadelphia PA USA"},{"name":"Department of Psychiatry and Human Behavior Jefferson Medical College Thomas Jefferson University  Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amber M.","family":"Holbrook","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Jefferson Medical College Thomas Jefferson University  Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mara G.","family":"Coyle","sequence":"additional","affiliation":[{"name":"Department of Pediatrics The Warren Alpert Medical School of Brown University  Providence RI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah H.","family":"Heil","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University of Vermont  Burlington VT USA"},{"name":"Department of Psychology University of Vermont  Burlington VT USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy L.","family":"Salisbury","sequence":"additional","affiliation":[{"name":"Department of Pediatrics The Warren Alpert Medical School of Brown University  Providence RI USA"},{"name":"Department of Pediatrics Women and Infant Hospital  Providence RI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan M.","family":"Stine","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavior Neurosciences Wayne State University  Detroit MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter R.","family":"Martin","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Pharmacology Vanderbilt University  Nashville TN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hendr\u00e9e E.","family":"Jones","sequence":"additional","affiliation":[{"name":"Departments of Psychiatry and Behavioral Sciences and Obstetrics and Gynecology Johns Hopkins University School of Medicine  Baltimore MD USA"},{"name":"Research Triangle Park NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,10,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.280.22.1936"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2005.08.010"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8545(05)70362-4"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/02791072.1994.10472263"},{"key":"e_1_2_6_6_1","first-page":"1367","volume-title":"Primary Pediatric Care","author":"Finnegan L. 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