{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T06:08:35Z","timestamp":1759990115517},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,12,22]],"date-time":"2004-12-22T00:00:00Z","timestamp":1103673600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:bold>Background<\/jats:bold> :\u2002The general therapeutic approach is the cornerstone in the management of irritable bowel syndrome, but the effect is poorly documented.<\/jats:p><jats:p><jats:bold>Aim<\/jats:bold> :\u2002To evaluate the effect of the general therapeutic approach for irritable bowel syndrome.<\/jats:p><jats:p><jats:bold>Methods<\/jats:bold> :\u2002Subjects with irritable bowel syndrome identified in a public screening were included. Scores for abdominal symptom (range 0\u201312), musculoskeletal pain and mood disorders were calculated. After exclusion of other disorders, a doctor presented irritable bowel syndrome as a positive diagnosis, gave information, reassurance and lifestyle advice, but no pharmacotherapy. A dietician gave dietary advice. There was a follow\u2010up after 6\u2003months.<\/jats:p><jats:p><jats:bold>Results<\/jats:bold> :\u2002Sixty\u2010five persons (females\/males: 44\/21) with mean age 49\u2003years (range 31\u201376) were included, 31 (48%) were recommended dietary changes. Twenty subjects (31%) had satisfactory relief of symptoms after 6\u2003months. The scores for abdominal symptom was reduced from 3.1 to 2.2 (<jats:italic>P<\/jats:italic>\u2003=\u20030.007), the reduction was 2.2 in the diarrhoea\u2010predominant group given advice compared with 0.4 in the other subjects (<jats:italic>P<\/jats:italic>\u2003=\u20030.035). Previous consultations for the complaints, visits for psychiatric disorders, and presence of mood disorders were predictors of persistent complaints.<\/jats:p><jats:p><jats:bold>Conclusions<\/jats:bold> :\u2002There was a significant relief of symptoms after 6\u2003months, those with psychological co\u2010morbidity responded less well. The effect of dietary advice was only seen in those with diarrhoea\u2010predominant irritable bowel syndrome.<\/jats:p>","DOI":"10.1111\/j.1365-2036.2004.02302.x","type":"journal-article","created":{"date-parts":[[2005,1,10]],"date-time":"2005-01-10T09:29:59Z","timestamp":1105349399000},"page":"21-27","source":"Crossref","is-referenced-by-count":12,"title":["The value of a general therapeutic approach in subjects with irritable bowel syndrome"],"prefix":"10.1111","volume":"21","author":[{"given":"K. W.","family":"Monsbakken","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. O.","family":"Vandvik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. G.","family":"Farup","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,12,22]]},"reference":[{"issue":"2","key":"e_1_2_14_2_2","first-page":"ii1","article-title":"British Society of Gastroenterology guidelines for the management of the irritable bowel syndrome","volume":"47","author":"Jones J","year":"2000","journal-title":"Gut"},{"key":"e_1_2_14_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2002.01312.x"},{"key":"e_1_2_14_4_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.37095"},{"key":"e_1_2_14_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8553(03)00022-0"},{"key":"e_1_2_14_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(99)00086-8"},{"key":"e_1_2_14_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/08039480310000932"},{"issue":"238","key":"e_1_2_14_8_2","first-page":"25","article-title":"Food intolerance, lactose malabsorption and dietary habits in persons with irritable bowel syndrome (IBS)","volume":"38","author":"Monsbakken K","year":"2003","journal-title":"Scand J Gastroenterol"},{"key":"e_1_2_14_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000051878"},{"key":"e_1_2_14_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200306000-00016"},{"key":"e_1_2_14_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-200207001-00009"},{"key":"e_1_2_14_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2001.00951.x"},{"key":"e_1_2_14_13_2","doi-asserted-by":"publisher","DOI":"10.1159\/000072061"},{"key":"e_1_2_14_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-277X.2001.00284.x"},{"key":"e_1_2_14_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0269-2813.2004.01862.x"},{"key":"e_1_2_14_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200012010-00008"},{"key":"e_1_2_14_17_2","doi-asserted-by":"publisher","DOI":"10.1080\/02813430310003282"},{"key":"e_1_2_14_18_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-277X.2003.00427.x"},{"key":"e_1_2_14_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7108.572"},{"key":"e_1_2_14_20_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2003.01523.x"},{"key":"e_1_2_14_21_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-122-2-199501150-00005"},{"key":"e_1_2_14_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07388.x"},{"key":"e_1_2_14_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2004.01929.x"},{"issue":"2","key":"e_1_2_14_24_2","first-page":"A\u201088","article-title":"Psychological symptoms do not predict symptom improvement in standard medical care for irritable bowel syndrome (IBS)","volume":"126","author":"Whitehead WE","year":"2004","journal-title":"Gastroenterology"},{"key":"e_1_2_14_25_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2003.01591.x"}],"container-title":["Alimentary Pharmacology &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2036.2004.02302.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2036.2004.02302.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T00:14:13Z","timestamp":1697242453000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2036.2004.02302.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12,22]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["10.1111\/j.1365-2036.2004.02302.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2036.2004.02302.x","archive":["Portico"],"relation":{},"ISSN":["0269-2813","1365-2036"],"issn-type":[{"value":"0269-2813","type":"print"},{"value":"1365-2036","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,12,22]]}}}