{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T02:26:04Z","timestamp":1770431164500,"version":"3.49.0"},"reference-count":32,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2005,4,22]],"date-time":"2005-04-22T00:00:00Z","timestamp":1114128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2005,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:bold>Background<\/jats:bold> :\u2002Studies suggest obstructive sleep apnea syndrome (OSAS) frequently manifests in patients with gastroesophageal reflux disease (GERD) and that there may be a causal relationship.<\/jats:p><jats:p><jats:bold>Aim<\/jats:bold> :\u2002To determine the relationship between OSAS and symptoms of GERD.<\/jats:p><jats:p><jats:bold>Methods<\/jats:bold> :\u2002Consecutive patients referred to the Sleep Disorders Center (SDC) 18 years and older with polysomnographically defined OSAS were evaluated prospectively for GERD using a validated symptoms questionnaire. The GERD and OSAS relationship was assessed by 1) determining frequency of GERD in patients with and without OSAS; 2) ascertaining the relationship between OSAS severity categories and presence of GERD; 3) examining GERD score in relation to those factors that might affect both GERD and OSAS, e.g. obesity.<\/jats:p><jats:p><jats:bold>Results<\/jats:bold> :\u2002One thousand and twenty\u2010three SDC patients met entry citeria. Amongst participants, GERD was common (29% of women and 17% of males) and OSAS extremely common (58% of women and 80% of males). GERD score did not correlate with OSAS variables. The severity of OSAS did not influence the prevalence of GERD.<\/jats:p><jats:p><jats:bold>Conclusion<\/jats:bold> :\u2002In a large group of patients referred to a sleep disorders center, there was no relationship between OSAS and GERD symptoms. Also, there was no relationship between the severity of OSAS and the likelihood of GERD symptoms.<\/jats:p>","DOI":"10.1111\/j.1365-2036.2005.02447.x","type":"journal-article","created":{"date-parts":[[2005,4,23]],"date-time":"2005-04-23T00:34:58Z","timestamp":1114216498000},"page":"1127-1133","source":"Crossref","is-referenced-by-count":48,"title":["Symptoms of gastro\u2010oesophageal reflux disease and the severity of obstructive sleep apnoea syndrome are not related in sleep disorders center patients"],"prefix":"10.1111","volume":"21","author":[{"given":"H.\u2010N.","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. D.","family":"Vorona","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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