{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T05:09:45Z","timestamp":1771909785719,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2005,6,9]],"date-time":"2005-06-09T00:00:00Z","timestamp":1118275200000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2005,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:bold>Background<\/jats:bold>:\u2002A colon free of faecal residue is required for accurate diagnostic colonoscopy. Patient tolerance of his\/her colonoscopy cathartic regimen affects patient compliance and willingness to undergo repeated examinations.<\/jats:p><jats:p><jats:bold>Aim<\/jats:bold>:\u2002To determine whether a meal could be consumed during standard bowel preparation.<\/jats:p><jats:p><jats:bold>Methods<\/jats:bold>:\u2002This was a randomized, endoscopists\u2019 blinded comparison of the tolerability and efficacy of a prepackaged, low\u2010residue diet (NutraPrep) combined with the LoSo Prep bowel cleansing system, which contains magnesium citrate, bisocodyl tablets and a bisocodyl suppository (NP\u2010LS regimen), compared with a clear liquid diet and a double\u2010dose sodium phosphate (Fleet Phospho\u2010soda) regimen (2F regimen). Outcome measures included efficacy of bowel preparation, patient preparation tolerability, side\u2010effects and patient safety.<\/jats:p><jats:p><jats:bold>Results<\/jats:bold>:\u2002A total of 506 patients completed the study, 222 randomized to 2F and 284 to NP\u2010LS. The NP\u2010LS regimen resulted in significantly better colon cleansing in terms of the proportion with good or excellent results (<jats:italic>P<\/jats:italic>\u2003=\u20030.025) and in significantly better patient tolerance and willingness to repeat the cathartic preparation (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.01).<\/jats:p><jats:p><jats:bold>Conclusion<\/jats:bold>:\u2002The NP\u2010LS regimen proved superior to the 2F regimen.<\/jats:p>","DOI":"10.1111\/j.1365-2036.2005.02494.x","type":"journal-article","created":{"date-parts":[[2005,6,9]],"date-time":"2005-06-09T11:23:20Z","timestamp":1118316200000},"page":"1491-1495","source":"Crossref","is-referenced-by-count":61,"title":["Efficacy of bowel preparation with the use of a prepackaged, low fibre diet with a low sodium, magnesium citrate cathartic vs. a clear liquid diet with a standard sodium phosphate cathartic"],"prefix":"10.1111","volume":"21","author":[{"given":"M.","family":"Delegge","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,9]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(02)70367-2"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(01)70087-9"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2000.108480"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2002.125361"},{"key":"e_1_2_7_6_2","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/S0016-5085(24)05135-7","article-title":"Comparison of colon cleansing methods in preparation for colonoscopy","volume":"86","author":"DiPalma J","year":"1984","journal-title":"Gastroenterology"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2003.318"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02055690"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02054117"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2001.119733"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-33207"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(98)70351-7"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.1996.53195000.x"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001610-200305000-00004"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(03)80006-8"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(97)70011-7"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2002.01295.x"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.40482.x"}],"container-title":["Alimentary Pharmacology &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2036.2005.02494.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2036.2005.02494.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T15:06:39Z","timestamp":1735743999000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2036.2005.02494.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6]]},"references-count":17,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2005,6]]}},"alternative-id":["10.1111\/j.1365-2036.2005.02494.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2036.2005.02494.x","archive":["Portico"],"relation":{},"ISSN":["0269-2813","1365-2036"],"issn-type":[{"value":"0269-2813","type":"print"},{"value":"1365-2036","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,6]]}}}