{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T10:00:19Z","timestamp":1776506419941,"version":"3.51.2"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,8,11]],"date-time":"2005-08-11T00:00:00Z","timestamp":1123718400000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2005,8]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:bold>Background:\u2002<\/jats:bold> The benefits of serologic screening for coeliac disease in asymptomatic individuals are debatable.<\/jats:p><jats:p><jats:bold>Aim:\u2002<\/jats:bold> To investigate dietary compliance, quality of life and bone mineral density after long\u2010term treatment in coeliac disease patients found by screening in risk groups.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> The study comprised 53 consecutive screen\u2010detected coeliac patients diagnosed 14\u2003years (median) ago. Dietary compliance was assessed by interview, 4\u2010day food record and serology. Quality of life was evaluated by the Psychological General Well\u2010Being and SF\u201036 questionnaires, gastrointestinal symptoms by the Gastrointestinal Symptom Rating Scale and bone mineral density by dual\u2010energy x\u2010ray absorptiometry. Comparisons were made to 44 symptom\u2010detected\u2010treated coeliac patients, 110 non\u2010coeliac subjects and the general population.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> A total of 96% of screen\u2010detected and 93% of symptom\u2010detected coeliac patients adhered to a strict or fairly strict gluten\u2010free diet. In screen\u2010detected patients, quality of life and gastrointestinal symptoms were similar to those in symptom\u2010detected patients or non\u2010coeliac controls and bone mineral density was similar to that in the general population.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Long\u2010term dietary compliance in screen\u2010detected patients was good. Quality of life and bone mineral density were comparable with those in non\u2010coeliac subjects and the general population. Active screening in coeliac disease risk groups seems to be reasonable rather than harmful.<\/jats:p>","DOI":"10.1111\/j.1365-2036.2005.02574.x","type":"journal-article","created":{"date-parts":[[2005,8,11]],"date-time":"2005-08-11T12:53:45Z","timestamp":1123764825000},"page":"317-324","source":"Crossref","is-referenced-by-count":98,"title":["Is coeliac disease screening in risk groups justified? 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