{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T09:48:31Z","timestamp":1761126511052},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,7,25]],"date-time":"2006-07-25T00:00:00Z","timestamp":1153785600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Antireflux surgery has been mainly evaluated in tertiary referral centres. Data regarding post\u2010operative outcome in non\u2010erosive reflux disease are lacking.<\/jats:p><jats:p><jats:bold>Aim\u2002<\/jats:bold> To assess long\u2010term outcome after antireflux surgery performed in a community practice setting.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> We selected consecutively 60 non\u2010erosive reflux disease patients and 61 erosive oesophagitis patients with symptomatic gastro\u2010oesophageal reflux disease. After surgery, each subject answered a validated disease\u2010specific health\u2010related quality of life questionnaire and another questionnaire focusing on symptoms, late morbidity and drug use.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> After a 43\u2010month median follow\u2010up, an excellent outcome was reported by less than two\u2010thirds of patients. Quality of life scores were lower in the non\u2010erosive reflux disease group, especially in female patients. Non\u2010erosive reflux disease patients reported more daily symptoms and more reflux\u2010related symptoms (<jats:italic>P<\/jats:italic>\u2003=\u20030.04). Proton\u2010pump inhibitor use was higher in non\u2010erosive reflux disease patients (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.005). Multivariate analysis identified four independent predictive factors associated with better outcome, namely male gender, abnormal preoperative acid exposure, a long duration of symptoms and surgical expertise.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> In community practice, the results of antireflux surgery are inferior to those reported by tertiary centres. Outcome seems poorer in non\u2010erosive reflux disease especially in female patients. Nearly one\u2010third of the non\u2010erosive reflux disease patients continue to take proton\u2010pump inhibitors. These results highlight the need for careful selection of patients before antireflux surgery.<\/jats:p>","DOI":"10.1111\/j.1365-2036.2006.03024.x","type":"journal-article","created":{"date-parts":[[2006,7,25]],"date-time":"2006-07-25T13:13:45Z","timestamp":1153833225000},"page":"621-632","source":"Crossref","is-referenced-by-count":21,"title":["Antireflux surgery for non\u2010erosive and erosive reflux disease in community practice"],"prefix":"10.1111","volume":"24","author":[{"given":"R.","family":"THIBAULT","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"CORON","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"S\u00c9BILLE","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"SACHER\u2010HUVELIN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"BRULEY DES VARANNES","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"GOURNAY","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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