{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T01:27:30Z","timestamp":1785806850538,"version":"3.56.0"},"reference-count":59,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,10,26]],"date-time":"2007-10-26T00:00:00Z","timestamp":1193356800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Prospective nationwide multicentre studies that have evaluated endoscopic findings and reflux symptoms using a well\u2010designed questionnaire are very rare.<\/jats:p><jats:p><jats:bold>Aim\u2002<\/jats:bold> To compare the prevalence rates of and risk factors for erosive oesophagitis and non\u2010erosive reflux disease (NERD) in the Korean population.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> A gastroscopic examination was performed on 25\u2003536 subjects who visited 40 Healthcare Centers for a health check\u2010up. A gastro\u2010oesophageal reflux questionnaire and multivariate analysis were used to determine the risk factors for erosive oesophagitis and NERD.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> 2019 (8%) and 996 subjects (4%) had erosive oesophagitis and non\u2010erosive reflux disease, respectively; only 58% of subjects with erosive oesophagitis had reflux symptoms. Multivariate analysis showed that the risk factors for erosive oesophagitis and NERD differed, i.e. those of erosive oesophagitis were male, a <jats:italic>Helicobacter pylori<\/jats:italic> eradication history, alcohol, body mass index \u226525 and hiatal hernia. In contrast, the risk factors for NERD were female, age &lt;40 and \u226560 vs. 40\u201359\u2003years, body mass index &lt;23 and a monthly income &lt;$1000, glucose \u2265126\u2003mg\/dL, smoking, a stooping posture at work and antibiotic usage.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> The prevalence rates of erosive oesophagitis and NERD were 8% and 4%, respectively, in Korean health check\u2010up subjects. The risk factors for erosive oesophagitis and NERD were found to differ, which indicates that their underlying pathogeneses are distinct.<\/jats:p>","DOI":"10.1111\/j.1365-2036.2007.03561.x","type":"journal-article","created":{"date-parts":[[2010,7,23]],"date-time":"2010-07-23T14:01:55Z","timestamp":1279893715000},"page":"173-185","source":"Crossref","is-referenced-by-count":157,"title":["The prevalence of and risk factors for erosive oesophagitis and non\u2010erosive reflux disease: a nationwide multicentre prospective study in Korea"],"prefix":"10.1111","volume":"27","author":[{"given":"N.","family":"KIM","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. W.","family":"LEE","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. I.","family":"CHO","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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