{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T14:40:54Z","timestamp":1770734454991,"version":"3.49.0"},"reference-count":24,"publisher":"Wiley","issue":"11-12","license":[{"start":{"date-parts":[[2010,10,5]],"date-time":"2010-10-05T00:00:00Z","timestamp":1286236800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:sec><jats:label\/><jats:p> <jats:italic>Aliment Pharmacol Ther<\/jats:italic> 2010; <jats:bold>32:<\/jats:bold> 1373\u20131382<\/jats:p><\/jats:sec><jats:sec><jats:title>Summary<\/jats:title><jats:p><jats:bold>Background\u2002<\/jats:bold> Although consensus guidelines for eosinophilic oesophagitis have been published, it remains unclear whether gastroenterologists follow these recommendations.<\/jats:p><jats:p><jats:bold>Aim\u2002<\/jats:bold> To assess academic and community practice patterns for the evaluation and treatment of eosinophilic oesophagitis and to compare these practices with current guidelines.<\/jats:p><jats:p><jats:bold>Methods\u2002<\/jats:bold> This was a prospective study of academic and community gastroenterologists using a self\u2010administered online survey.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> A total of 60% (34 of 57) of academic and 29% (38 of 133) of community gastroenterologists completed the survey. Only 24% of academic and 3% of community gastroenterologists follow consensus guidelines to diagnose eosinophilic oesophagitis (<jats:italic>P<\/jats:italic>\u2003=\u20030.007). A proton pump inhibitor trial or negative pH study prior to diagnosis was required by just 25% of all gastroenterologists. A majority (60%) do not use the recommended threshold of 15 eosinophils per high powered field to diagnosis eosinophilic oesophagitis. Half (51%) mistakenly require a positive endoscopic finding. For first\u2010line treatment, about half of the gastroenterologists surveyed treat with a swallowed topical steroid (53% academic, 56% community; <jats:italic>P\u2003<\/jats:italic>=\u2003N.S.), consistent with the guidelines.<\/jats:p><jats:p><jats:bold>Conclusions\u2002<\/jats:bold> There is variability in practice patterns for both diagnosis and treatment of eosinophilic oesophagitis. Ongoing education and research concerning diagnosis and treatment are needed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1365-2036.2010.04476.x","type":"journal-article","created":{"date-parts":[[2010,10,5]],"date-time":"2010-10-05T09:07:29Z","timestamp":1286269649000},"page":"1373-1382","source":"Crossref","is-referenced-by-count":59,"title":["Practice patterns for the evaluation and treatment of eosinophilic oesophagitis"],"prefix":"10.1111","volume":"32","author":[{"given":"A. F.","family":"Peery","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. J.","family":"Shaheen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. S.","family":"Dellon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,10,5]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.08.017"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200408263510924"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2009.06.023"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2004.11.006"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.107714"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2009.08.030"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2009.01307.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01396.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004065.pub3"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01179.x"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.87"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-009-0951-9"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01296781"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2050.2009.01019.x"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.08.033"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2007.11.008"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.05.001"},{"issue":"1","key":"e_1_2_6_19_2","first-page":"A104","article-title":"Budesonide as induction treatment for active eosinophilic esophagitis in adolescents and adults: a randomized, double\u2010blind, placebo\u2010controlled study (Bee\u2010I trial)","volume":"134","author":"Straumann A","year":"2008","journal-title":"Gastroenterology"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.07.048"},{"issue":"1","key":"e_1_2_6_21_2","article-title":"In esophageal squamous epithelial cell lines from patients with eosinophilic esophagitis (EoE), omeprazole blocks the stimulated secretion of eotaxin\u20103: a potential anti\u2010inflammatory effect of omeprazole in EoE that is independent of acid inhibition","volume":"138","author":"Zhang X","year":"2010","journal-title":"Gastroenterology"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-009-0801-9"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.47"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2009.03935.x"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2010.101"}],"container-title":["Alimentary Pharmacology &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2036.2010.04476.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2036.2010.04476.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T05:17:35Z","timestamp":1693459055000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2036.2010.04476.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,5]]},"references-count":24,"journal-issue":{"issue":"11-12","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["10.1111\/j.1365-2036.2010.04476.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2036.2010.04476.x","archive":["Portico"],"relation":{},"ISSN":["0269-2813","1365-2036"],"issn-type":[{"value":"0269-2813","type":"print"},{"value":"1365-2036","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,5]]}}}