{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T14:07:33Z","timestamp":1793196453973,"version":"4.5.0"},"reference-count":37,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1618,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1111\/j.1365-2036.2011.04640.x","type":"journal-article","created":{"date-parts":[[2011,3,28]],"date-time":"2011-03-28T11:18:34Z","timestamp":1301311114000},"page":"1215-1224","source":"Crossref","is-referenced-by-count":195,"title":["Functional dyspepsia impairs quality of life in the adult population"],"prefix":"10.1111","volume":"33","author":[{"given":"P.","family":"Aro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. J.","family":"Talley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Agr\u00e9us","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.-E.","family":"Johansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Bolling-Sternevald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Storskrubb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Ronkainen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,3,28]]},"reference":[{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB1|cit1","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1136\/bmj.298.6665.30","article-title":"Prevalence of symptoms of dyspepsia in the community","volume":"298","author":"Jones","year":"1989","journal-title":"BMJ"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB2|cit2","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1111\/j.1572-0241.2002.05783.x","article-title":"Epidemiology and health care seeking in the functional GI disorders: a population-based study","volume":"97","author":"Koloski","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB3|cit3","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1080\/00365520410008141","article-title":"Valid symptom reporting at upper endoscopy in a random sample of the Swedish adult general population. The Kalixanda study","volume":"39","author":"Aro","year":"2004","journal-title":"Scand J Gastroenterol"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB4|cit4","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.cger.2007.06.003","article-title":"Chronic gastrointestinal symptoms in the elderly","volume":"23","author":"Crane","year":"2007","journal-title":"Clin Geriatr Med"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB5|cit5","volume-title":"The Functional Gastrointestinal Disorders","author":"Drossman","year":"1994"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB6|cit6","volume-title":"ROME II. The Functional Gastrointestinal Disorders","author":"Drossman","year":"2000"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB7|cit7","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1053\/j.gastro.2005.11.059","article-title":"Functional gastroduodenal disorders","volume":"130","author":"Tack","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB8|cit8","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1136\/gut.2005.078634","article-title":"Functional dyspepsia, delayed gastric emptying, and impaired quality of life","volume":"55","author":"Talley","year":"2006","journal-title":"Gut"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB9|cit9","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3109\/00365529609095547","article-title":"Quality of life in functional dyspepsia","volume":"221","author":"Talley","year":"1996","journal-title":"Scand J Gastroenterol Suppl"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB10|cit10","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S1550-8579(08)80009-5","article-title":"Functional dyspepsia affects women more than men in daily life: a case-control study in primary care","volume":"5","author":"Wel\u00e9n","year":"2008","journal-title":"Gend Med"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB11|cit11","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1111\/j.1365-2036.2008.03619.x","article-title":"Impairment of health-related quality of life in functional dyspepsia and chronic liver disease: the influence of depression and anxiety","volume":"27","author":"Haag","year":"2008","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB12|cit12","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/j.1365-2982.2009.01415.x","article-title":"Is there any association between disturbed gastrointestinal visceromotor and sensory function and impaired quality of life in functional dyspepsia?","volume":"22","author":"Haag","year":"2010","journal-title":"Neurogastroenterol Motil"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB13|cit13","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1097\/00042737-200311000-00005","article-title":"Quality of life in patients with functional dyspepsia: a prospective 1-year follow-up study in Spanish patients","volume":"15","author":"Gutierrez","year":"2003","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB14|cit14","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1080\/00365520701204204","article-title":"Concomitant functional dyspepsia and irritable bowel syndrome decrease health-related quality of life in gastroesophageal reflux disease","volume":"42","author":"De Vries","year":"2007","journal-title":"Scand J Gastroenterol"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB15|cit15","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.0269-2813.2004.01807.x","article-title":"Impact of functional gastrointestinal disorders on health-related quality of life: a population-based case-control study","volume":"19","author":"Halder","year":"2004","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB16|cit16","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1111\/j.1440-1746.2010.06249.x","article-title":"Prevalence of overlaps between GERD, FD and IBS and impact on health-related quality of life","volume":"25","author":"Kaji","year":"2010","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB17|cit17","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.genhosppsych.2010.05.002","article-title":"Depressive mood and quality of life in functional gastrointestinal disorders: differences between functional dyspepsia, irritable bowel syndrome and overlap syndrome","volume":"32","author":"Lee","year":"2010","journal-title":"Gen Hosp Psych"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB18|cit18","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1053\/j.gastro.2009.03.039","article-title":"Anxiety is associated with uninvestigated and functional dyspepsia (Rome III Criteria) in a Swedish population-based study","volume":"37","author":"Aro","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB19|cit19","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1111\/j.1365-2036.2006.02952.x","article-title":"Gastro-oesophageal reflux symptoms and health-related quality of life in the adult general population - the Kalixanda study","volume":"23","author":"Ronkainen","year":"2006","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB20|cit20","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1016\/j.cgh.2007.05.015","article-title":"Non-ulcer dyspepsia and duodenal eosinophilia: an adult endoscopic population-based case-control study","volume":"5","author":"Talley","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB21|cit21","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1111\/j.1365-2036.2009.03937.x","article-title":"Duodenla mastocytosis, eosinophilia and intraepithelial lymphocytosis as possible disease markers in the irritable bowel syndrome and functional dyspepsia","volume":"29","author":"Walker","year":"2009","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB22|cit22","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1136\/gut.30.7.893","article-title":"Dyspeptic symptoms in the community","volume":"30","author":"Jones","year":"1989","journal-title":"Gut"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB23|cit23","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1093\/fampra\/10.2.152","article-title":"Socio-economic factors, health care consumption and rating of abdominal symptom severity. A report from The Abdominal Symptom Study","volume":"10","author":"Agr\u00e9us","year":"1993","journal-title":"Fam Pract"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB24|cit24","doi-asserted-by":"crossref","first-page":"252","DOI":"10.3109\/02813439308994840","article-title":"Reproducibility and validity of a postal questionnaire. The abdominal symptom study","volume":"11","author":"Agr\u00e9us","year":"1993","journal-title":"Scand J Prim Health Care"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB25|cit25","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1080\/00365520410008132","article-title":"Validation of the translation and cross-cultural adaptation into Finnish of the Abdominal Symptom Questionnaire, the Hospital Anxiety and Depression Scale and the Complaint Score Questionnaire","volume":"39","author":"Aro","year":"2004","journal-title":"Scand J Gastroenterol"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB26|cit26","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1046\/j.1365-2036.2003.01706.x","article-title":"Health-related quality of life in functional dyspepsia","volume":"18","author":"El-Serag","year":"2003","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB27|cit27","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1016\/0277-9536(95)00125-Q","article-title":"The Swedish SF-36 Health Survey-I. Evaluation of data quality, scaling assumptions, rerliability and construct valitity across generall populations in Sweden","volume":"41","author":"Sullivan","year":"1995","journal-title":"Soc Sci Med"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB28|cit28","volume-title":"SF-36 Health Survey: Manual and Interpretation Guide","author":"Ware","year":"1993"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB29|cit29","unstructured":"Committee for Medicinal Products for Human Use Guideline on the choice of the non-inferiority margin (EMEA\/CPMP\/EWP\/2158\/99) http:\/\/www.ema.europa.eu\/docs\/eu_GB\/document_library\/Scientific_guideline\/2009\/09\/WC500003636.pdf"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB30|cit30","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1080\/00365520510011579","article-title":"High prevalence of gastroesophageal reflux symptoms and esophagitis with or without symptoms in the general adult Swedish population: a Kalixanda study report","volume":"40","author":"Ronkainen","year":"2005","journal-title":"Scand J Gastroenterol"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB31|cit31","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1111\/j.1572-0241.2006.00630.x","article-title":"The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus","volume":"101","author":"Vakil","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB32|cit32","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1080\/003655200750024308","article-title":"Identifying dyspepsia and irritable bowel syndrome: the value of pain or discomfort, and bowel habit descriptors","volume":"35","author":"Agr\u00e9us","year":"2000","journal-title":"Scand J Gastroenterol"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB33|cit33","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1038\/ajg.2008.122","article-title":"An evidence-based position statement on the management of irritable bowel syndrome","volume":"104","author":"Brandt","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB34|cit34","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"Zigmond","year":"1983","journal-title":"Acta Psychiatr Scand"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB35|cit35","volume-title":"The Intercoold STATA 8 Program","author":"StataCorp","year":"2003"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB36|cit36","first-page":"3534","article-title":"SF-36-terveyskysely koetun terveyden ja toimintakyvyn mittarina","volume":"51","author":"Hagman","year":"1996","journal-title":"Suomen L\u00e4\u00e4k\u00e4rilehti"},{"key":"10.1111\/j.1365-2036.2011.04640.x-BIB37|cit37","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1093\/aje\/kwj129","article-title":"Peptic ulcer disease in a general adult population. The Kalixanda study: a random population-based study","volume":"163","author":"Aro","year":"2006","journal-title":"Am J Epidemiol"}],"container-title":["Alimentary Pharmacology & Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2036.2011.04640.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1365-2036.2011.04640.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T17:38:02Z","timestamp":1625420282000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2036.2011.04640.x"}},"subtitle":["Functional dyspepsia and quality of life"],"short-title":[],"issued":{"date-parts":[[2011,3,28]]},"references-count":37,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2011,6]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1365-2036.2011.04640.x","relation":{},"ISSN":["0269-2813"],"issn-type":[{"value":"0269-2813","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3,28]]}}}