{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:53:39Z","timestamp":1787014419873,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,1,16]],"date-time":"2012-01-16T00:00:00Z","timestamp":1326672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Aliment Pharmacol Ther"],"published-print":{"date-parts":[[2012,3]]},"abstract":"Summary<\/jats:title>\n \n Background<\/jats:title>\n \n Functional dyspepsia (\n FD<\/jats:styled-content>\n ) is a common disease without an established optimal treatment.\n <\/jats:p>\n <\/jats:sec>\n \n Aim<\/jats:title>\n \n To determine (i) the effect of acupuncture in relieving\n FD<\/jats:styled-content>\n symptoms and improving life quality; (ii) the effect difference between acupoint and non\u2010acupoint; and (iii) the effect difference among different acupoints.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A total of 712 eligible patients were included and randomly assigned to six groups (Group\n A<\/jats:styled-content>\n : specific acupoints of the stomach meridian; Group\n B<\/jats:styled-content>\n : non\u2010specific acupoints of the stomach meridian; Group\n C<\/jats:styled-content>\n : specific acupoints of alarm and transport points; Group\n D<\/jats:styled-content>\n : specific acupoints of the gallbladder meridian; Group\n E<\/jats:styled-content>\n : sham acupuncture of non\u2010acupoints; and Group\n F<\/jats:styled-content>\n : itopride). A treatment period of 4\u00a0weeks (continuous five sessions per week), and a follow\u2010up period of 12\u00a0weeks were arranged. The outcomes were the (i) patients\u2019 response, (ii) symptoms improvement measured using the\n S<\/jats:styled-content>\n ymptom\n I<\/jats:styled-content>\n ndex of\n D<\/jats:styled-content>\n yspepsia and (iii) quality\u2010of\u2010life improvement based on\n N<\/jats:styled-content>\n epean\n D<\/jats:styled-content>\n yspepsia\n I<\/jats:styled-content>\n ndex.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n All groups had an improvement in dyspepsia symptoms and the\n Q<\/jats:styled-content>\n o\n L<\/jats:styled-content>\n at the end of treatment, and the improvement was sustained for 4\u00a0weeks and 12\u00a0weeks. The overall response rate was significantly higher in acupuncture group\n A<\/jats:styled-content>\n (70.69%), and lower in sham acupuncture group (34.75%), compared with itopride and other acupuncture groups. Similarly, the difference in symptoms and\n Q<\/jats:styled-content>\n o\n L<\/jats:styled-content>\n improvement was significant between group\n A<\/jats:styled-content>\n and the other acupuncture groups.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Acupuncture is effective in the treatment of functional dyspepsia, and is superior to non\u2010acupoint puncture. The benefit of acupuncture relies on acupoint specificity.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/j.1365-2036.2011.04979.x","type":"journal-article","created":{"date-parts":[[2012,1,16]],"date-time":"2012-01-16T01:58:33Z","timestamp":1326679113000},"page":"552-561","source":"Crossref","is-referenced-by-count":109,"title":["Randomised clinical trial: an assessment of acupuncture on specific meridian or specific acupoint vs. sham acupuncture for treating functional dyspepsia"],"prefix":"10.1111","volume":"35","author":[{"given":"T. T.","family":"Ma","sequence":"first","affiliation":[{"name":"Teaching Hospital of Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Y.","family":"Yu","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Li","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. R.","family":"Liang","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X. P.","family":"Tian","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Zheng","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Yan","sequence":"additional","affiliation":[{"name":"Hunan University of Traditional Chinese Medicine Changsha Hunan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. J.","family":"Sun","sequence":"additional","affiliation":[{"name":"Hubei University of Traditional Chinese Medicine Wuhan Hubei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X. R.","family":"Chang","sequence":"additional","affiliation":[{"name":"Hunan University of Traditional Chinese Medicine Changsha Hunan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Zhao","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Wu","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Zeng","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,1,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.11.059"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i17.2661"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-009-0168-x"},{"key":"e_1_2_6_5_1","first-page":"CD001960","article-title":"Pharmacological interventions for non\u2010ulcer dyspepsia","volume":"18","author":"Moayyedi P","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-199345060-00005"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2004.02196.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2008.11.007"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v13.i25.3417"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38512.405440.8F"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-145-1-200607040-00005"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6215-10-75"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2009.01424.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.71.129"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.01363.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.3173"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.1999.00445.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa052639"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6215-10-123"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.136"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2006.04493.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-006-1773-6"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.156"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2005.074518"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v11.i26.4040"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2008.0369"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2001.62.178"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21805"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2009.07.015"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.03.039"}],"container-title":["Alimentary Pharmacology & Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2036.2011.04979.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2036.2011.04979.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T21:10:49Z","timestamp":1695503449000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2036.2011.04979.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,16]]},"references-count":29,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["10.1111\/j.1365-2036.2011.04979.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2036.2011.04979.x","archive":["Portico"],"relation":{},"ISSN":["0269-2813","1365-2036"],"issn-type":[{"value":"0269-2813","type":"print"},{"value":"1365-2036","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,16]]}}}