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Twenty\u2010four hours after uneventful anaesthesia and surgery, the patient developed myocardial infarction and cardiogenic shock. Immediate percutaneous transluminal coronary angioplasty, intra aortic balloon counterpulsation, and catecholamine therapy failed to stabilise haemodynamics. In light of successful reperfusion therapy and an only moderate elevation of troponin I, myocardial stunning rather than myonecrosis was considered to be the major contributor to life\u2010threatening left ventricular failure. Therefore, the calcium\u2010sensitising drug levosimendan, which exerts positive inotropic activity without increasing myocardial oxygen demand, was administered as a rescue medication. Within 24\u2003h, levosimendan resulted in decreased filling pressures, reduced left ventricular end\u2010diastolic volume, and augmented systemic pressures. Seven days following surgery, the patient was discharged from the intensive care unit in good clinical condition.<\/jats:p>","DOI":"10.1111\/j.1365-2044.2005.04431.x","type":"journal-article","created":{"date-parts":[[2005,12,15]],"date-time":"2005-12-15T15:12:52Z","timestamp":1134659572000},"page":"61-63","source":"Crossref","is-referenced-by-count":17,"title":["Levosimendan: a promising treatment for myocardial stunning?"],"prefix":"10.1111","volume":"61","author":[{"given":"B. M.","family":"Ellger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. K.","family":"Zahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. 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The Study of Perioperative Ischemia Research Group","volume":"268","author":"Mangano DT","year":"1992","journal-title":"Journal of the American Medical Association"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-9842(02)00041-7"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.20.2141"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(97)00057-6"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200161050-00006"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/00001573-200205000-00008"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.2001.3158"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)09455-2"}],"container-title":["Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2044.2005.04431.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:54:10Z","timestamp":1761699250000},"score":1,"resource":{"primary":{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2044.2005.04431.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12,15]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,1]]}},"alternative-id":["10.1111\/j.1365-2044.2005.04431.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2044.2005.04431.x","archive":["Portico"],"relation":{},"ISSN":["0003-2409","1365-2044"],"issn-type":[{"type":"print","value":"0003-2409"},{"type":"electronic","value":"1365-2044"}],"subject":[],"published":{"date-parts":[[2005,12,15]]}}}