{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T23:12:49Z","timestamp":1793747569898,"version":"4.6.1"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2007,5,14]],"date-time":"2007-05-14T00:00:00Z","timestamp":1179100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    This prospective, randomised, double blind study compared the efficacy of pethidine as an adjuvant to bupivacaine with the efficacy of bupivacaine alone for infra\u2010orbital nerve block in alleviating postoperative pain in children undergoing cleft lip repair. Forty paediatric patients aged between 5 and 60\u2003months undergoing cleft lip repair were randomly allocated to two groups of 20. After tracheal intubation, group B received bilateral intra\u2010oral, infra\u2010orbital nerve block with 1\u2003ml of 0.25% bupivacaine on each side and group P received 1\u2003ml of 0.25% bupivacaine along with 0.25\u2003mg.kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    body weight pethidine. Sedation after recovery from anaesthesia was assessed using the University of Michigan Sedation Scale (UMSS) and pain was assessed postoperatively up to 36\u2003h using the FLACC scale (Face, Legs, Activity, Cry, Consolability). The median (IQR) duration of analgesia from the time of administration of block in group B was 18\u2003h (14.2\u201320) compared to 29.1\u2003h (24\u201336) in group P (p\u2003\n                    <jats:italic>=<\/jats:italic>\n                    \u20030.001). Addition of pethidine as an adjunct to local anaesthetic significantly prolonged the duration of postoperative analgesia without any adverse effects.\n                  <\/jats:p>","DOI":"10.1111\/j.1365-2044.2007.05028.x","type":"journal-article","created":{"date-parts":[[2007,5,14]],"date-time":"2007-05-14T05:46:20Z","timestamp":1179121580000},"page":"581-585","source":"Crossref","is-referenced-by-count":27,"title":["Bilateral intra\u2010oral, infra\u2010orbital nerve block for postoperative analgesia following cleft lip repair in paediatric patients: comparison of bupivacaine vs bupivacaine\u2013pethidine combination"],"prefix":"10.1111","volume":"62","author":[{"given":"N.","family":"Jonnavithula","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Durga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. 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