{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T02:12:24Z","timestamp":1776132744426,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,2,15]],"date-time":"2007-02-15T00:00:00Z","timestamp":1171497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Animal Genetics"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Exocrine pancreatic insufficiency is considered an inherited disease in several dog breeds. Affected dogs show polyphagia, weight loss and voluminous faeces of light colour due to the lack of pancreatic enzymes. In the study described herein, we performed a segregation analysis using the <jats:sc>singles<\/jats:sc> method for three families of the Eurasian dog breed. Our data were consistent with an autosomal recessive mode of inheritance. In addition, we performed a linkage analysis in these families using four microsatellite markers on CFA3 and two microsatellites on CFA23. Based on our results, we excluded the canine orthologs of the human <jats:italic>cholecystokinin<\/jats:italic> (<jats:italic>CCK<\/jats:italic>) and the <jats:italic>cholecystokinin A receptor<\/jats:italic> (<jats:italic>CCKAR<\/jats:italic>) genes as candidates for exocrine pancreatic insufficiency.<\/jats:p>","DOI":"10.1111\/j.1365-2052.2007.01570.x","type":"journal-article","created":{"date-parts":[[2007,2,16]],"date-time":"2007-02-16T12:54:17Z","timestamp":1171630457000},"page":"171-173","source":"Crossref","is-referenced-by-count":11,"title":["SHORT COMMUNICATION: Exocrine pancreatic insufficiency in the Eurasian dog breed \u2013 inheritance and exclusion of two candidate genes"],"prefix":"10.1111","volume":"38","author":[{"given":"H. F.","family":"Proschowsky","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Fredholm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,2,15]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02071316"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.189401"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00335-005-0076-1"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.1979.tb00683.x"},{"key":"e_1_2_3_6_1","volume-title":"Documentation for CRI\u2010MAP","author":"Green P","year":"1990"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0831002100"},{"key":"e_1_2_3_8_1","volume-title":"Der Eurasier","author":"Hoffmann J.","year":"1987"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200101253440405"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1006\/geno.1997.4749"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2002.63.1429"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1119(86)90339-2"},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1993.1610"},{"key":"e_1_2_3_14_1","first-page":"157","article-title":"Erbanalytische Untersuchungen \u00fcber die chronische exokrine Pankreasinsuffizienz beim Deutschen Sch\u00e4ferhund","volume":"119","author":"Weber V.","year":"1977","journal-title":"Schweizer Archiv f\u00fcr Tierheilkunde"},{"key":"e_1_2_3_15_1","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1186\/BF03546871","article-title":"The hereditary nature of canine pancreatic degenerative dtrophy in the German Shepherd dog","volume":"21","author":"Westermarck E.","year":"1980","journal-title":"Acta Veterinaria Scandinavica"},{"key":"e_1_2_3_16_1","first-page":"195","article-title":"Sensitivity and specificity of radioimmunoassay of serum trypsin\u2010like immunoreactivity for the diagnosis of canine exocrine pancreatic insufficiency","volume":"192","author":"Williams D.A.","year":"1988","journal-title":"Journal of the American Veterinary Medical Association"}],"container-title":["Animal Genetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2052.2007.01570.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2052.2007.01570.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T08:52:33Z","timestamp":1697187153000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2052.2007.01570.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2,15]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["10.1111\/j.1365-2052.2007.01570.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2052.2007.01570.x","archive":["Portico"],"relation":{},"ISSN":["0268-9146","1365-2052"],"issn-type":[{"value":"0268-9146","type":"print"},{"value":"1365-2052","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,2,15]]}}}