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In the past 4\u00a0years, considerable advances have been made in the characterization of the genomic architecture of <jats:styled-content style=\"fixed-case\">CNV<\/jats:styled-content> in domestic species. First, low\u2010resolution <jats:styled-content style=\"fixed-case\">CNV<\/jats:styled-content> maps were produced for cattle, goat, sheep, pig, dog, chicken, duck and turkey, showing that these structural polymorphisms comprise a significant part of these genomes. Furthermore, <jats:styled-content style=\"fixed-case\">CNV<\/jats:styled-content>s have been associated with several pigmentation (white coat in horse, pig and sheep) and morphological (late feathering and pea comb in chicken) traits, as well as with susceptibility to a wide array of diseases and developmental disorders, for example osteopetrosis, anhidrotic ectodermal dysplasia, copper toxicosis, intersexuality, cone degeneration, periodic fever and dermoid sinus, among others. In the future, development of high\u2010resolution tools for <jats:styled-content style=\"fixed-case\">CNV<\/jats:styled-content> detection and typing combined with the implementation of databases integrating <jats:styled-content style=\"fixed-case\">CNV<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> QTL<\/jats:styled-content> and gene expression data will be essential to identify and measure the impact of this source of structural variation on the many phenotypes that are relevant to animal breeders and veterinary practitioners.<\/jats:p>","DOI":"10.1111\/j.1365-2052.2012.02317.x","type":"journal-article","created":{"date-parts":[[2012,3,7]],"date-time":"2012-03-07T04:38:44Z","timestamp":1331095124000},"page":"503-517","source":"Crossref","is-referenced-by-count":131,"title":["Copy number variation in the genomes of domestic animals"],"prefix":"10.1111","volume":"43","author":[{"given":"A.","family":"Clop","sequence":"first","affiliation":[{"name":"Department of 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