{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:11:27Z","timestamp":1760217087319},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[1981,10,1]],"date-time":"1981-10-01T00:00:00Z","timestamp":370742400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1981,10,1]]},"abstract":"<jats:title>SUMMARY<\/jats:title><jats:p>An apparently hitherto undescribed ectodermal dysplasia\/malformation syndrome is presented. The patient, the last son in an outbred sibship of four males, presents scalp hypotrichosis, aplasia cutis congenita of the scalp, dental abnormalities, onychodysplasia, dry skin with hypochromic and atrophic (poikiloderma-like) spots with vicarious (marginal) hyperchromia, unusual facies, asymmetrical skull, absent right nipple, irregular areolae, palmar keratosis, dermatoglyphic alterations, syndactyly, clinodactyly, phalangeal aplasias and hypoplasias, right leukoma, abnormal EEG, and other findings. The aetiology is unknown. A review of seventeen ectodermal dysplasias is presented for differential diagnosis.<\/jats:p>","DOI":"10.1111\/j.1365-2133.1981.tb00768.x","type":"journal-article","created":{"date-parts":[[2006,7,30]],"date-time":"2006-07-30T09:46:52Z","timestamp":1154252812000},"page":"371-382","source":"Crossref","is-referenced-by-count":34,"title":["A previously undescribed condition: tricho-odonto-onycho-dermal syndrome. A review of the tricho-odonto-onychial subgroup of ectodermal dysplasias"],"prefix":"10.1093","volume":"105","author":[{"given":"MARTA","family":"PINHEIRO","sequence":"first","affiliation":[{"name":"Departments of Genetics and Dermatology, Federal University of Paran\u00e1, Curitiba, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.C.","family":"PEREIRA","sequence":"additional","affiliation":[{"name":"Departments of Genetics and Dermatology, Federal University of Paran\u00e1, Curitiba, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"FREIRE-MAIA","sequence":"additional","affiliation":[{"name":"Departments of Genetics and Dermatology, Federal University of Paran\u00e1, Curitiba, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[1981,10,1]]},"reference":[{"key":"2023012703560641900_b1","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1365-4362.1973.tb00056.x","article-title":"A new dental, ocular and cutaneous syndrome","volume":"12","author":"Ackerman","year":"1973","journal-title":"International Journal of Dermatology"},{"key":"2023012703560641900_b2","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1002\/ajpa.1330380305","article-title":"Taurodont, pyramidal and fused molar roots associated with other anomalies in a kindred","volume":"38","author":"Ackerman","year":"1973","journal-title":"American Journal of Physical Anthropology"},{"issue":"suppl.","key":"2023012703560641900_b3","first-page":"535","article-title":"Um novo syndrome autoss\u00f4mico recessive de displasia ectod\u00ebrmica e malforma\u00e7\u00f6o","volume":"32","author":"Alves","year":"1980","journal-title":"Ci\u00eancia e Cultura"},{"key":"2023012703560641900_b4","volume-title":"An autosomal recessive ectodermal dysplasia syndrome of hypotrichosis, onychodysplasia, hyperkeratosis, kyphoscoliosis, cataract and other manifestations. 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Human Heredity","author":"C\u00f4t\u00e9","year":"1981"},{"key":"2023012703560641900_b11","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1001\/archderm.1965.01600150019003","article-title":"The genetics of incontinentia pigmenti","volume":"92","author":"Curth","year":"1965","journal-title":"Archives of Dermatology"},{"key":"2023012703560641900_b12","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1136\/adc.15.82.65","article-title":"A syndrome characterized by ectodermal dysplasia, polydactyly, chondro-dysplasia and congenital morbus cordis. Report of three cases","volume":"15","author":"Ellis","year":"1940","journal-title":"Archives of Diseases of Children"},{"issue":"13","key":"2023012703560641900_b13","article-title":"Normal values for selected physical parameters: an aid tosyndrome delineation","volume":"Vol. X","author":"Feingold","year":"1974","journal-title":"Birth Defects: Original Article Series"},{"key":"2023012703560641900_b14","first-page":"50","article-title":"Ein Fall von erblicher Haararmut und die Art ihrer Vererbung. 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