{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T20:05:10Z","timestamp":1789157110126,"version":"build-2803163510"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1743,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1111\/j.1365-2133.2010.10037.x","type":"journal-article","created":{"date-parts":[[2010,9,16]],"date-time":"2010-09-16T06:45:25Z","timestamp":1284619525000},"page":"182-186","source":"Crossref","is-referenced-by-count":32,"title":["Peroxisome proliferator-activated receptor activators protect sebocytes from apoptosis: a new treatment modality for acne?"],"prefix":"10.1093","volume":"164","author":[{"given":"M.","family":"Schuster","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.C.","family":"Zouboulis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Ochsendorf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Tha\u00e7i","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Bernd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Kaufmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Kippenberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2010,11,23]]},"reference":[{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB1|cit1","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1038\/jid.2009.47","article-title":"Prevalence, severity and severity risk factors of acne in high school pupils: a community-based study","volume":"129","author":"Ghodsi","year":"2009","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB2|cit2","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.clindermatol.2004.03.004","article-title":"Acne and sebaceous gland function","volume":"22","author":"Zouboulis","year":"2004","journal-title":"Clin Dermatol"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB3|cit3","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1586\/17469872.2.6.693","article-title":"Isotretinoin: state of the art treatment for acne vulgaris","volume":"2","author":"Ganceviciene","year":"2007","journal-title":"Expert Rev Dermatol"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB4|cit4","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1046\/j.1523-1747.1999.00487.x","article-title":"Rat preputial sebocyte differentiation involves peroxisome proliferator-activated receptors","volume":"112","author":"Rosenfield","year":"1999","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB5|cit5","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1046\/j.1523-1747.2003.12411.x","article-title":"Expression of peroxisome proliferator-activated receptor and CCAAT\/enhancer binding protein transcription factors in cultured human sebocytes","volume":"121","author":"Chen","year":"2003","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB6|cit6","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1111\/j.1365-2133.2004.06171.x","article-title":"Peroxisome proliferator-activated receptor and farnesoid X receptor ligands differentially regulate sebaceous differentiation in human sebaceous gland organ cultures in vitro","volume":"151","author":"Downie","year":"2004","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB7|cit7","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s00109-005-0715-8","article-title":"Enzymes involved in the biosynthesis of leukotriene B4 and prostaglandin E2 are active in sebaceous glands","volume":"84","author":"Alestas","year":"2006","journal-title":"J Mol Med"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB8|cit8","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/j.1365-2133.2006.07671.x","article-title":"Testosterone metabolism to 5\u03b1-dihydrotestosterone and synthesis of sebaceous lipids is regulated by the peroxisome proliferator-activated receptor ligand linoleic acid in human sebocytes","volume":"156","author":"Makrantonaki","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB9|cit9","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1038\/sj.jid.5700336","article-title":"Peroxisome proliferator-activated receptors increase human sebum production","volume":"126","author":"Trivedi","year":"2006","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB10|cit10","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1046\/j.1523-1747.2003.12029.x","article-title":"Differentiation and apoptosis in human immortalized sebocytes","volume":"120","author":"Wr\u00f3bel","year":"2003","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB11|cit11","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1046\/j.1523-1747.1999.00771.x","article-title":"Establishment and characterization of an immortalized human sebaceous gland cell line (SZ95)","volume":"113","author":"Zouboulis","year":"1999","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB12|cit12","doi-asserted-by":"crossref","first-page":"3060","DOI":"10.1074\/jbc.M409590200","article-title":"Mechanical stretch stimulates protein kinase B\/Akt phosphorylation in epidermal cells via angiotensin II type 1 receptor and epidermal growth factor receptor","volume":"280","author":"Kippenberger","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB13|cit13","doi-asserted-by":"crossref","first-page":"4189","DOI":"10.1210\/endo.142.10.8446","article-title":"Up-regulation of uncoupling protein 3 gene expression by fatty acids and agonists for PPARs in L6 myotubes","volume":"142","author":"Son","year":"2001","journal-title":"Endocrinology"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB14|cit14","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1046\/j.1523-1747.1999.00584.x","article-title":"UVB activates ERK1\/2 and p38 signaling pathways via reactive oxygen species in cultured keratinocytes","volume":"112","author":"Peus","year":"1999","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB15|cit15","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1016\/j.bbamcr.2010.03.009","article-title":"Ligation of beta4 integrins activates PKB\/Akt and ERK1\/2 by distinct pathways - relevance of the keratin filament","volume":"1803","author":"Kippenberger","year":"2010","journal-title":"Biochim Biophys Acta"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB16|cit16","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1124\/jpet.106.115758","article-title":"Neuroprotective efficacy of the peroxisome proliferator-activated receptor delta-selective agonists in vitro and in vivo","volume":"320","author":"Iwashita","year":"2007","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB17|cit17","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1681\/ASN.2004090802","article-title":"Peroxisome proliferator-activated receptor beta\/gamma exerts a strong protection from ischemic acute renal failure","volume":"16","author":"Letavernier","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/j.1365-2133.2010.10037.x-BIB18|cit18","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1046\/j.0022-202x.2001.01537.x","article-title":"Activators of peroxisome proliferator-activated receptors protect human skin from ultraviolet-B-light-induced inflammation","volume":"117","author":"Kippenberger","year":"2001","journal-title":"J Invest Dermatol"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2133.2010.10037.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1365-2133.2010.10037.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T13:50:07Z","timestamp":1676382607000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/164\/1\/182\/6642965"}},"subtitle":["PPAR activators protect SZ95 sebocytes from apoptosis"],"short-title":[],"issued":{"date-parts":[[2010,11,23]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1365-2133.2010.10037.x","relation":{},"ISSN":["0007-0963"],"issn-type":[{"value":"0007-0963","type":"print"}],"subject":[],"published":{"date-parts":[[2010,11,23]]}}}