{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T14:06:45Z","timestamp":1794492405633,"version":"4.9.1"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1568,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1111\/j.1365-2133.2011.10254.x","type":"journal-article","created":{"date-parts":[[2011,2,17]],"date-time":"2011-02-17T09:49:56Z","timestamp":1297936196000},"page":"1292-1298","source":"Crossref","is-referenced-by-count":441,"title":["Elevated levels of tumour necrosis factor (TNF)-\u03b1, interleukin (IL)-1\u03b2 and IL-10 in hidradenitis suppurativa skin: a rationale for targeting TNF-\u03b1 and IL-1\u03b2"],"prefix":"10.1093","volume":"164","author":[{"given":"H.H.","family":"van der Zee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"de Ruiter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.G.","family":"van den Broecke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.A.","family":"Dik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.D.","family":"Laman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.P.","family":"Prens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2011,5,17]]},"reference":[{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB1|cit1","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0190-9622(96)90321-7","article-title":"The prevalence of hidradenitis suppurativa and its potential precursor lesions","volume":"35","author":"Jemec","year":"1996","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB2|cit2","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.jaad.2008.06.020","article-title":"Prevalence and factors associated with hidradenitis suppurativa: results from two case-control studies","volume":"59","author":"Revuz","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB3|cit3","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.jaad.2006.08.061","article-title":"Quality of life impairment in hidradenitis suppurativa: a study of 61 cases","volume":"56","author":"Wolkenstein","year":"2007","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB4|cit4","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1046\/j.1365-2133.2001.04137.x","article-title":"Morbidity in patients with hidra-denitis suppurativa","volume":"144","author":"von der Werth","year":"2001","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB5|cit5","doi-asserted-by":"crossref","first-page":"264","DOI":"10.2340\/00015555-0866","article-title":"Psychophysical aspects of hidradenitis suppurativa","volume":"90","author":"Matusiak","year":"2010","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB6|cit6","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.jaad.2008.11.911","article-title":"Hidradenitis suppurativa: a comprehensive review","volume":"60","author":"Alikhan","year":"2009","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB7|cit7","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/j.1365-2230.1996.tb00145.x","article-title":"Hidradenitis suppurativa - characteristics and consequences","volume":"21","author":"Jemec","year":"1996","journal-title":"Clin Exp Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB8|cit8","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1365-2133.2009.09430.x","article-title":"Hidradenitis suppurativa and inflammatory bowel disease: are they associated? Results of a pilot study","volume":"162","author":"van der Zee","year":"2010","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB9|cit9","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1016\/S0140-6736(02)08512-4","article-title":"Maintenance infliximab for Crohn\u2019s disease: the ACCENT I randomised trial","volume":"359","author":"Hanauer","year":"2002","journal-title":"Lancet"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB10|cit10","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/j.1365-2133.2007.08332.x","article-title":"Long-term efficacy of a single course of infliximab in hidradenitis suppurativa","volume":"158","author":"Mekkes","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB11|cit11","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.jaad.2008.11.898","article-title":"A prospective clinical trial of open-label etanercept for the treatment of hidradenitis suppurativa","volume":"60","author":"Lee","year":"2009","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB12|cit12","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.jaad.2009.06.050","article-title":"Infliximab therapy for patients with moderate to severe hidradenitis suppurativa: a randomized, double-blind, placebo-controlled crossover trial","volume":"62","author":"Grant","year":"2010","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB13|cit13","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1111\/j.1365-2133.2007.08372.x","article-title":"An open-label phase II study of the safety and efficacy of etanercept for the therapy of hidradenitis suppurativa","volume":"158","author":"Giamarellos-Bourboulis","year":"2008","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB14|cit14","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1001\/archdermatol.2010.72","article-title":"Treatment of hidradenitis suppurativa with etanercept injection","volume":"146","author":"Adams","year":"2010","journal-title":"Arch Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB15|cit15","volume-title":"Dermatologic Surgery","author":"Roenigk","year":"1989"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB16|cit16","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/(SICI)1096-9896(199902)187:3<358::AID-PATH253>3.0.CO;2-8","article-title":"IL-1 beta and IFN-gamma induce the regenerative epidermal phenotype of psoriasis in the transwell skin organ culture system. IFN-gamma up-regulates the expression of keratin 17 and keratinocyte transglutaminase via endogenous IL-1 production","volume":"187","author":"Wei","year":"1999","journal-title":"J Pathol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB17|cit17","doi-asserted-by":"crossref","first-page":"601","DOI":"10.2340\/00015555-0749","article-title":"Increased serum tumour necrosis factor-alpha in hidradenitis suppurativa patients: is there a basis for treatment with anti-tumour necrosis factor-alpha agents?","volume":"89","author":"Matusiak","year":"2009","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB18|cit18","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1365-2133.2006.07556.x","article-title":"Altered innate and adaptive immune responses in patients with hidradenitis suppurativa","volume":"156","author":"Giamarellos-Bourboulis","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB19|cit19","doi-asserted-by":"crossref","first-page":"595","DOI":"10.2340\/00015555-0747","article-title":"Treatment of hidradenitis suppurativa with tumour necrosis factor-alpha inhibitors","volume":"89","author":"Haslund","year":"2009","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB20|cit20","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1159\/000213064","article-title":"Lymph nodes in hidradenitis suppurativa","volume":"219","author":"Wortsman","year":"2009","journal-title":"Dermatology"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB21|cit21","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1111\/j.1365-2133.1996.tb03880.x","article-title":"Hidradenitis suppurativa or acne inversa. A clinicopathological study of early lesions","volume":"135","author":"Boer","year":"1996","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB22|cit22","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/nri2691","article-title":"The IL-1 family: regulators of immunity","volume":"10","author":"Sims","year":"2010","journal-title":"Nat Rev Immunol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB23|cit23","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.cell.2010.01.040","article-title":"The inflammasomes","volume":"140","author":"Schroder","year":"2010","journal-title":"Cell"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB24|cit24","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/nri2711","article-title":"The regulation of IL-10 production by immune cells","volume":"10","author":"Saraiva","year":"2010","journal-title":"Nat Rev Immunol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB25|cit25","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.4049\/jimmunol.1000017","article-title":"Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages","volume":"185","author":"Filardy","year":"2010","journal-title":"J Immunol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB26|cit26","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1111\/j.1365-2133.2010.10034.x","article-title":"Hidradenitis suppurativa\/acne inversa: bilocated epithelial hyperplasia with very different sequelae","volume":"164","author":"von Laffert","year":"2011","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10254.x-BIB27|cit27","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/s003840050159","article-title":"Extent of surgery and recurrence rate of hidradenitis suppurativa","volume":"13","author":"Ritz","year":"1998","journal-title":"Int J Colorectal Dis"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2133.2011.10254.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1365-2133.2011.10254.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T08:51:25Z","timestamp":1676364685000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/164\/6\/1292\/6644328"}},"subtitle":["Elevated TNF-\u03b1, IL-1\u03b2 and IL-10 in hidradenitis suppurativa"],"short-title":[],"issued":{"date-parts":[[2011,5,17]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1365-2133.2011.10254.x","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.724197501.793501399","asserted-by":"object"}]},"ISSN":["0007-0963"],"issn-type":[{"value":"0007-0963","type":"print"}],"subject":[],"published":{"date-parts":[[2011,5,17]]}}}