{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T09:33:14Z","timestamp":1769938394973,"version":"3.49.0"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1465,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1111\/j.1365-2133.2011.10463.x","type":"journal-article","created":{"date-parts":[[2011,6,21]],"date-time":"2011-06-21T12:29:34Z","timestamp":1308659374000},"page":"552-562","source":"Crossref","is-referenced-by-count":56,"title":["IgG-induced clustering of desmogleins 1 and 3 in skin of patients with pemphigus fits with the desmoglein nonassembly depletion hypothesis"],"prefix":"10.1093","volume":"165","author":[{"given":"D.A.M.","family":"Oktarina","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"van der Wier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.F.H.","family":"Diercks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.F.","family":"Jonkman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.H.","family":"Pas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2011,8,28]]},"reference":[{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB1|cit1","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/0092-8674(91)90360-B","article-title":"Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion","volume":"67","author":"Amagai","year":"1991","journal-title":"Cell"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB2|cit2","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1172\/JCI111426","article-title":"Distinction between epidermal antigens binding pemphigus vulgaris and pemphigus foliaceus autoantibodies","volume":"74","author":"Stanley","year":"1984","journal-title":"J Clin Invest"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB3|cit3","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.4049\/jimmunol.136.4.1227","article-title":"A monoclonal antibody to the desmosomal glycoprotein desmoglein I binds the same polypeptide as human autoantibodies in pemphigus foliaceus","volume":"136","author":"Stanley","year":"1986","journal-title":"J Immunol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB4|cit4","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1172\/JCI117349","article-title":"Absorption of pathogenic autoantibodies by the extracellular domain of pemphigus vulgaris antigen (Dsg3) produced by baculovirus","volume":"94","author":"Amagai","year":"1994","journal-title":"J Clin Invest"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB5|cit5","doi-asserted-by":"crossref","first-page":"133","DOI":"10.2302\/kjm.51.133","article-title":"Pemphigus as a paradigm of autoimmunity and cell adhesion","volume":"51","author":"Amagai","year":"2002","journal-title":"Keio J Med"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB6|cit6","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1172\/JCI5252","article-title":"Explanations for the clinical and microscopic localization of lesions in pemphigus foliaceus and vulgaris","volume":"103","author":"Mahoney","year":"1999","journal-title":"J Clin Invest"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB7|cit7","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1172\/JCI115968","article-title":"Autoantibodies against the amino-terminal cadherin-like binding domain of pemphigus vulgaris antigen are pathogenic","volume":"90","author":"Amagai","year":"1992","journal-title":"J Clin Invest"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB8|cit8","doi-asserted-by":"crossref","first-page":"23778","DOI":"10.1074\/jbc.M501365200","article-title":"Desmosome signaling. Inhibition of p38MAPK prevents pemphigus vulgaris IgG-induced cytoskeleton reorganization","volume":"280","author":"Berkowitz","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB9|cit9","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1001\/archderm.140.3.327","article-title":"Pemphigus vulgaris acantholysis ameliorated by cholinergic agonists","volume":"140","author":"Nguyen","year":"2004","journal-title":"Arch Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB10|cit10","doi-asserted-by":"crossref","first-page":"18303","DOI":"10.1074\/jbc.M710046200","article-title":"Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin-and dynamin-independent mechanism","volume":"283","author":"Delva","year":"2008","journal-title":"J Biol Chem"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB11|cit11","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1038\/sj.jid.5701248","article-title":"Outside-in signaling through integrins and cadherins: a central mechanism to control epidermal growth and differentiation?","volume":"128","author":"Muller","year":"2008","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB12|cit12","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1038\/sj.jid.5700735","article-title":"Nuclear c-Myc: a molecular marker for early stage pemphigus vulgaris","volume":"127","author":"Williamson","year":"2007","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB13|cit13","doi-asserted-by":"crossref","first-page":"7623","DOI":"10.1074\/jbc.M512447200","article-title":"Desmoglein endocytosis and desmosome disassembly are coordinated responses to pemphigus autoantibodies","volume":"281","author":"Calkins","year":"2006","journal-title":"J Biol Chem"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB14|cit14","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1111\/j.1365-2133.2010.09672.x","article-title":"Binding of pemphigus vulgaris IgG to antigens in desmosome core domains excludes immune complexes rather than directly splitting desmosomes","volume":"162","author":"Aoyama","year":"2010","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB15|cit15","first-page":"74","volume-title":"Diagnostic Immunohistochemistry of the Skin","author":"Nousari","year":"1998"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB16|cit16","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/j.1365-2133.1993.tb00192.x","article-title":"An immunohistological study of desmosomal components in pemphigus","volume":"128","author":"Burge","year":"1993","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB17|cit17","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1001\/archderm.129.5.596","article-title":"Autoimmune pemphigus. A distinct staining pattern with an anti-desmoglein antibody","volume":"129","author":"Carlotti","year":"1993","journal-title":"Arch Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB18|cit18","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1309\/3CAKPEU8JXGWLEDC","article-title":"Immunostaining with antibodies to desmoglein provides the diagnosis of drug-induced pemphigus and allows prediction of outcome","volume":"130","author":"Maruani","year":"2008","journal-title":"Am J Clin Pathol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB19|cit19","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/j.1365-2133.2004.06006.x","article-title":"U-serrated immunodeposition pattern differentiates type VII collagen targeting bullous diseases from other subepidermal bullous autoimmune diseases","volume":"151","author":"Vodegel","year":"2004","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB20|cit20","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1111\/j.1600-0625.2007.00557.x","article-title":"Plakoglobin-dependent disruption of the desmosomal plaque in pemphigus vulgaris","volume":"16","author":"de Bruin","year":"2007","journal-title":"Exp Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB21|cit21","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s00403-007-0754-9","article-title":"Intraperitoneal injection of pemphigus vulgaris-IgG into mouse depletes epidermal keratinocytes of desmoglein 3 associated with generation of acantholysis","volume":"299","author":"Shu","year":"2007","journal-title":"Arch Dermatol Res"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB22|cit22","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1038\/jid.2008.339","article-title":"Disruption of desmosome assembly by monovalent human pemphigus vulgaris monoclonal antibodies","volume":"129","author":"Mao","year":"2009","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB23|cit23","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1046\/j.1523-1747.1999.00463.x","article-title":"Pemphigus vulgaris-IgG causes a rapid depletion of desmoglein 3 (Dsg3) from the Triton X-100 soluble pools, leading to the formation of Dsg3-depleted desmosomes in a human squamous carcinoma cell line, DJM-1 cells","volume":"112","author":"Aoyama","year":"1999","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB24|cit24","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jdermsci.2005.09.001","article-title":"Pemphigus vulgaris-IgG reduces the desmoglein 3\/desmocollin 3 ratio on the cell surface in cultured keratinocytes as revealed by double-staining immunoelectron microscopy","volume":"40","author":"Shu","year":"2005","journal-title":"J Dermatol Sci"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB25|cit25","doi-asserted-by":"crossref","first-page":"17866","DOI":"10.1074\/jbc.M607963200","article-title":"Anti-desmoglein 3 (Dsg3) monoclonal antibodies deplete desmosomes of Dsg3 and differ in their Dsg3-depleting activities related to pathogenicity","volume":"282","author":"Yamamoto","year":"2007","journal-title":"J Biol Chem"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB26|cit26","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1046\/j.1523-1747.2001.01512.x","article-title":"Isoform-specific differences in the size of desmosomal cadherin\/catenin complexes","volume":"117","author":"Bannon","year":"2001","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB27|cit27","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1002\/(SICI)1521-4141(199907)29:07<2233::AID-IMMU2233>3.0.CO;2-4","article-title":"A pathogenic autoantibody, pemphigus vulgaris-IgG, induces phosphorylation of desmoglein 3, and its dissociation from plakoglobin in cultured keratinocytes","volume":"29","author":"Aoyama","year":"1999","journal-title":"Eur J Immunol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB28|cit28","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1080\/08916930600971943","article-title":"Pathogenic monoclonal antibody against desmoglein 3 augments desmoglein 3 and p38 MAPK phosphorylation in human squamous carcinoma cell line","volume":"39","author":"Kawasaki","year":"2006","journal-title":"Autoimmunity"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB29|cit29","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jaad.2009.05.016","article-title":"Disadhesion of epidermal keratinocytes: a histologic clue to palmoplantar keratodermas caused by DSG1 mutations","volume":"62","author":"Bergman","year":"2009","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB30|cit30","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1083\/jcb.200809044","article-title":"Desmoglein 1-dependent suppression of EGFR signaling promotes epidermal differentiation and morphogenesis","volume":"185","author":"Getsios","year":"2009","journal-title":"J Cell Biol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB31|cit31","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1038\/jid.1964.159","article-title":"An electron microscopic study of acantholysis and dyskeratosis in pemphigus foliaceus: with a special note on peculiar intracytoplasmic bodies","volume":"43","author":"Wilgram","year":"1964","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB32|cit32","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1111\/1523-1747.ep12284041","volume":"93","author":"Futamura","year":"1989","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB33|cit33","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/jid.1967.86","article-title":"An electron microscopic study on pemphigus vulgaris of the mouth and the skin with special reference to the intercellular cement","volume":"48","author":"Hashimoto","year":"1967","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB34|cit34","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/1523-1747.ep12274679","article-title":"Experimentally induced pemphigus vulgaris in neonatal BALB\/c mice: a time-course study of clinical, immunologic, ultrastructural, and cytochemical changes","volume":"84","author":"Takahashi","year":"1985","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB35|cit35","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.jaad.2005.12.003","article-title":"A novel explanation for acantholysis in pemphigus vulgaris: the basal cell shrinkage hypothesis","volume":"54","author":"Bystryn","year":"2006","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB36|cit36","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s00441-003-0812-3","article-title":"Continual assembly of desmosomes within stable intercellular contacts of epithelial A-431 cells","volume":"314","author":"Gloushankova","year":"2003","journal-title":"Cell Tissue Res"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB37|cit37","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1242\/jcs.115.8.1717","article-title":"Desmosomes: interconnected calcium-dependent structures of remarkable stability with significant integral membrane protein turnover","volume":"115","author":"Windoffer","year":"2002","journal-title":"J Cell Sci"},{"key":"10.1111\/j.1365-2133.2011.10463.x-BIB38|cit38","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1111\/j.1365-2133.2008.08971.x","article-title":"The ultrastructure of acantholysis in pemphigus vulgaris","volume":"160","author":"Diercks","year":"2009","journal-title":"Br J Dermatol"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2133.2011.10463.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1365-2133.2011.10463.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T15:19:50Z","timestamp":1686151190000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/165\/3\/552\/6644264"}},"subtitle":["Pemphigus deposition patterns"],"short-title":[],"issued":{"date-parts":[[2011,8,28]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,9]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1365-2133.2011.10463.x","relation":{},"ISSN":["0007-0963"],"issn-type":[{"value":"0007-0963","type":"print"}],"subject":[],"published":{"date-parts":[[2011,8,28]]}}}