{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T04:10:07Z","timestamp":1793419807802,"version":"4.5.0"},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":1317,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1111\/j.1365-2133.2011.10662.x","type":"journal-article","created":{"date-parts":[[2011,10,3]],"date-time":"2011-10-03T18:21:30Z","timestamp":1317666090000},"page":"279-287","source":"Crossref","is-referenced-by-count":127,"title":["The fatty acid profile of the skin surface lipid layer in papulopustular rosacea"],"prefix":"10.1093","volume":"166","author":[{"given":"S.","family":"N\u00ed Raghallaigh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Bender","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Lacey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Brennan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.C.","family":"Powell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2012,1,23]]},"reference":[{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB1|cit1","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1365-2133.1976.tb04365.x","article-title":"Skin surface lipid composition in rosacea","volume":"94","author":"Pye","year":"1976","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB2|cit2","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1067\/mjd.2002.120625","article-title":"Standard classification of rosacea: report of the National Rosacea Society Expert Committee on the Classification and Staging of Rosacea","volume":"46","author":"Wilkin","year":"2002","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB3|cit3","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1111\/j.1365-2133.1994.tb08590.x","article-title":"Determination of density of follicles on various regions of the face by cyanoacrylate biopsy: correlation with sebum output","volume":"131","author":"Pagnoni","year":"1994","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB4|cit4","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1016\/S0161-6420(82)34669-2","article-title":"Classification of chronic blepharitis","volume":"89","author":"McCulley","year":"1982","journal-title":"Ophthalmology"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB5|cit5","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0014-4835(03)00005-8","article-title":"Minocycline effect on meibomian gland lipids in meibomianitis patients","volume":"76","author":"Shine","year":"2003","journal-title":"Exp Eye Res"},{"issue":"3 Suppl.","key":"10.1111\/j.1365-2133.2011.10662.x-BIB6|cit6","first-page":"9","article-title":"Rosacea and the pilosebaceous follicle","volume":"74","author":"Powell","year":"2004","journal-title":"Cutis"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB7|cit7","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1159\/000079884","article-title":"The histopathology of rosacea: \u2018where\u2019s the beef?\u2019","volume":"209","author":"Powell","year":"2004","journal-title":"Dermatology"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB8|cit8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000249558","article-title":"T-cell subsets in acne rosacea lesions and the possible role of Demodex folliculorum","volume":"169","author":"Rufli","year":"1984","journal-title":"Dermatologica"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB9|cit9","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1046\/j.1468-3083.2001.00331.x","article-title":"Increased density of Demodex folliculorum and evidence of delayed hypersensitivity reaction in subjects with papulopustular rosacea","volume":"15","author":"Georgala","year":"2001","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB10|cit10","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1111\/j.1365-4362.1986.tb04533.x","article-title":"Treatment of rosacea with isotretinoin","volume":"25","author":"Hoting","year":"1986","journal-title":"Int J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB11|cit11","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2340\/00015555641521","article-title":"13-cis-Retinoic acid in rosacea. Clinical and laboratory findings","volume":"64","author":"Schmidt","year":"1984","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB12|cit12","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/1523-1747.ep12260695","article-title":"Control of free fatty acids in human surface lipids by Corynebacterium acnes","volume":"56","author":"Marples","year":"1971","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB13|cit13","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1001\/archdermatol.2010.196","article-title":"Retrospective analysis of the association between Demodex infestation and rosacea","volume":"146","author":"Zhao","year":"2010","journal-title":"Arch Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB14|cit14","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1159\/000323009","article-title":"Demodex mites - commensals, parasites or mutualistic organisms?","volume":"222","author":"Lacey","year":"2011","journal-title":"Dermatology"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB15|cit15","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1111\/j.1365-2133.2004.05985.x","article-title":"Epithelial barrier function and atopic diathesis in rosacea and perioral dermatitis","volume":"150","author":"Dirshka","year":"2004","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB16|cit16","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1080\/000155599750009915","article-title":"Stinging and rosacea","volume":"79","author":"Lonne-Rahm","year":"1999","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB17|cit17","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1111\/j.1600-0625.2008.00725.x","article-title":"Frontiers in sebaceous gland biology and pathology","volume":"17","author":"Zouboulis","year":"2008","journal-title":"Exp Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB18|cit18","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1038\/nm1616","article-title":"Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea","volume":"13","author":"Yamasaki","year":"2007","journal-title":"Nat Med"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB19|cit19","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1038\/sj.jid.5701235","article-title":"Sebocytes express functional cathelicidin antimicrobial peptides and can act to kill Propionibacterium acnes","volume":"128","author":"Lee","year":"2008","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB20|cit20","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1016\/j.micinf.2006.04.001","article-title":"Propionibacterium acnes and lipopolysaccharide induce the expression of antimicrobial peptides and proinflammatory cytokines\/chemokines in human sebocytes","volume":"8","author":"Nagy","year":"2006","journal-title":"Microbes Infect"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB21|cit21","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1194\/jlr.R700016-JLR200","article-title":"Thematic review series: skin lipids. Antimicrobial lipids at the skin surface","volume":"49","author":"Drake","year":"2008","journal-title":"J Lipid Res"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB22|cit22","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1159\/000069757","article-title":"Palmitoleic acid isomer (C16:1delta6) in human skin sebum is effective against Gram-positive bacteria","volume":"16","author":"Wille","year":"2003","journal-title":"Skin Pharmacol Appl Skin Physiol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB23|cit23","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1038\/jid.2009.384","article-title":"Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating beta-defensin-2 expression","volume":"130","author":"Nakatsuji","year":"2010","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB24|cit24","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.jaad.2004.01.048","article-title":"Standard grading system for rosacea: report of the National Rosacea Society Expert Committee on the Classification and Staging of Rosacea","volume":"50","author":"Wilkin","year":"2004","journal-title":"J Am Acad Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB25|cit25","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1111\/1523-1747.ep12696640","article-title":"Measurement of sebum output using a lipid absorbent tape","volume":"87","author":"Nordstrom","year":"1986","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB26|cit26","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1159\/000029945","article-title":"EEMCO guidance for the in vivo assessment of skin greasiness","volume":"13","author":"Pi\u00e9rard","year":"2000","journal-title":"Skin Pharmacol Appl Skin Physiol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB27|cit27","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1126\/science.186.4158.19","article-title":"Skin lipids: their biochemical uniqueness","volume":"186","author":"Nicolaides","year":"1974","journal-title":"Science"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB28|cit28","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/1523-1747.ep12676793","article-title":"Synthesis and composition of surface lipids of human skin","volume":"62","author":"Downing","year":"1974","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB29|cit29","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/1523-1747.ep12280318","article-title":"Anatomical variation in the amount and composition of human skin surface lipid","volume":"54","author":"Greene","year":"1970","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB30|cit30","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1152\/physrev.1989.69.2.383","article-title":"Control and function of sebaceous glands","volume":"69","author":"Thody","year":"1989","journal-title":"Physiol Rev"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB31|cit31","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/B978-0-12-024924-4.50013-4","article-title":"Chemistry and function of mammalian sebaceous lipids","volume":"24","author":"Stewart","year":"1991","journal-title":"Adv Lipid Res"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB32|cit32","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1046\/j.1523-1747.2003.12123.x","article-title":"Identification of the delta-6 desaturase of human sebaceous glands: expression and enzyme activity","volume":"120","author":"Ge","year":"2003","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB33|cit33","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jdermsci.2007.11.005","article-title":"The effect of a low glycaemic load diet on acne vulgaris and the fatty acid composition of skin surface triglycerides","volume":"50","author":"Smith","year":"2008","journal-title":"J Dermatol Sci"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB34|cit34","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1111\/1523-1747.ep12456856","article-title":"Dilutional effect of increased sebaceous gland activity on the proportion of linoleic acid in sebaceous wax esters and in epidermal acylceramides","volume":"87","author":"Stewart","year":"1986","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB35|cit35","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/1523-1747.ep12532793","article-title":"Effects of aging on fatty acids in skin surface lipids","volume":"73","author":"Nazzaro-Porro","year":"1979","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB36|cit36","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1016\/S0022-2275(20)34422-9","article-title":"Lateral chain packing in lipids and membranes","volume":"25","author":"Small","year":"1984","journal-title":"J Lipid Res"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB37|cit37","doi-asserted-by":"crossref","first-page":"111","DOI":"10.7150\/ijbs.3.111","article-title":"Essential role of Elovl4 in very long chain fatty acid synthesis, skin permeability barrier function, and neonatal survival","volume":"3","author":"Cameron","year":"2007","journal-title":"Int J Biol Sci"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB38|cit38","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/1523-1747.ep12514648","article-title":"Abnormalities in epidermal lipid metabolism in patients with atopic dermatitis","volume":"96","author":"Sch\u00e4fer","year":"1991","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB39|cit39","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1046\/j.1523-1747.2002.01833.x","article-title":"Deficiency of epidermal protein-bound omega-hydroxyceramides in atopic dermatitis","volume":"119","author":"Macheleidt","year":"2002","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB40|cit40","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1146\/annurev.bi.63.070194.004253","article-title":"Genetic and biochemical studies of protein N-myristoylation","volume":"63","author":"Johnson","year":"1994","journal-title":"Annu Rev Biochem"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB41|cit41","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1111\/1523-1747.ep12340135","article-title":"Optimization of physiological lipid mixtures for barrier repair","volume":"106","author":"Man","year":"1996","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB42|cit42","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1194\/jlr.R700013-JLR200","article-title":"Thematic review series: skin lipids. The role of epidermal lipids in cutaneous permeability barrier homeostasis","volume":"48","author":"Feingold","year":"2007","journal-title":"J Lipid Res"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB43|cit43","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/1523-1747.ep12482300","article-title":"Octadecadienoic acids in the skin surface lipids of acne patients and normal subjects","volume":"66","author":"Morello","year":"1976","journal-title":"J Invest Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB44|cit44","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1046\/j.0022-202x.2001.01612.x","article-title":"Metabolic fate and selective utilization of major fatty acids in human sebaceous gland","volume":"118","author":"Pappas","year":"2002","journal-title":"J Invest Dermatol"},{"issue":"Suppl. 1","key":"10.1111\/j.1365-2133.2011.10662.x-BIB45|cit45","first-page":"25","article-title":"The cutaneous microenvironment in papulopustular rosacea","volume":"161","author":"N\u00ed Raghallaigh","year":"2009","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB46|cit46","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/j.1365-2133.2007.08028.x","article-title":"Mite-related bacterial antigens stimulate inflammatory cells in rosacea","volume":"157","author":"Lacey","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1111\/j.1365-2133.2011.10662.x-BIB47|cit47","first-page":"S54","article-title":"Doxycycline modifies sebum production in-vitro","volume":"130","author":"N\u00ed Raghallaigh","year":"2010","journal-title":"J Invest Dermatol"}],"container-title":["British Journal of Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2133.2011.10662.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1365-2133.2011.10662.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T06:41:17Z","timestamp":1712990477000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjd\/article\/166\/2\/279\/6613610"}},"subtitle":["Fatty acid profile in papulopustular rosacea"],"short-title":[],"issued":{"date-parts":[[2012,1,23]]},"references-count":47,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1365-2133.2011.10662.x","relation":{},"ISSN":["0007-0963"],"issn-type":[{"value":"0007-0963","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1,23]]}}}