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The theoretical basis for potential alternative strategies for primary prevention of neurological injury in SCA is also discussed. These strategies will include, but will not be limited to: immunizations to prevent bacterial infections, particularly in low income countries; management of elevated blood pressure; and targeted strategies to increase baseline haemoglobin levels with therapies such as hyroxycarbamide or potentially definitive haematopoietic stem cell transplant.<\/jats:p>","DOI":"10.1111\/j.1365-2141.2011.09005.x","type":"journal-article","created":{"date-parts":[[2012,1,9]],"date-time":"2012-01-09T07:45:30Z","timestamp":1326095130000},"page":"14-25","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Prospects for primary stroke prevention in children with sickle cell anaemia"],"prefix":"10.1111","volume":"157","author":[{"given":"Lori C.","family":"Jordan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James 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