{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:25:55Z","timestamp":1760981155432},"reference-count":7,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,4,27]],"date-time":"2006-04-27T00:00:00Z","timestamp":1146096000000},"content-version":"vor","delay-in-days":9127,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Experimental Allergy"],"published-print":{"date-parts":[[1981,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>A simple filter paper technique for estimating nasal secretory activity (NSA) was studied in 179 healthy adults. The technique was reproducible and NSA correlated independently with age and race (<jats:italic>P<\/jats:italic> &lt; 0.001 in each case) but not with sex or smoking habits. Subjects with a past history of atopic disease (asthma, rhinitis or eczema) produced significantly more nasal secretion than those without such a history (<jats:italic>P<\/jats:italic>&lt;0.03). Among the former there was no significant difference in quantity of secretion recovered between those with and those without a past history of rhinitis.<\/jats:p><jats:p>Increased NSA appears to be a marker of the atopic state and its measurement could be of value in the management of patients with allergic nasal disorders.<\/jats:p>","DOI":"10.1111\/j.1365-2222.1981.tb01596.x","type":"journal-article","created":{"date-parts":[[2006,4,28]],"date-time":"2006-04-28T12:38:39Z","timestamp":1146227919000},"page":"287-292","source":"Crossref","is-referenced-by-count":26,"title":["A standardized filter paper technique for assessing nasal secretory activity"],"prefix":"10.1111","volume":"11","author":[{"given":"G. K.","family":"KNOWLES","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"TOWNSEND","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"TURNER\u2010WARWICK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,4,27]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"537","volume-title":"Histopathology of the Ear, Nose and Throat","author":"Eggston A.E.","year":"1947"},{"key":"e_1_2_1_3_1","volume-title":"The Natural History of Chronic Bronchitis and Emphysema","author":"Fletcher C.M.","year":"1976"},{"key":"e_1_2_1_4_1","first-page":"275","article-title":"Quantitative Composition of Nasal Secretions in Normal Subjects","volume":"80","author":"Lorin M.I.","year":"1972","journal-title":"Journal of Laboratory and Clinical Medicine"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000231383"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016487609120888"},{"key":"e_1_2_1_7_1","first-page":"41","volume-title":"Nasal Allergy","author":"MYGIND N.","year":"1978"},{"key":"e_1_2_1_8_1","first-page":"97","volume-title":"Nasal Physiology and Defence of the Lungs","author":"Proctor D. F.","year":"1977"}],"container-title":["Clinical &amp; Experimental Allergy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1365-2222.1981.tb01596.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1365-2222.1981.tb01596.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T12:38:00Z","timestamp":1699706280000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1365-2222.1981.tb01596.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,5]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1981,5]]}},"alternative-id":["10.1111\/j.1365-2222.1981.tb01596.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1365-2222.1981.tb01596.x","archive":["Portico"],"relation":{},"ISSN":["0954-7894","1365-2222"],"issn-type":[{"value":"0954-7894","type":"print"},{"value":"1365-2222","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,5]]}}}