{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:35:31Z","timestamp":1791200131538,"version":"4.2.0"},"reference-count":43,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2004,9,10]],"date-time":"2004-09-10T00:00:00Z","timestamp":1094774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Experimental Allergy"],"published-print":{"date-parts":[[2004,10]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    <jats:bold>Aim<\/jats:bold>\n                    To estimate the prevalence of self\u2010reported drug allergy in adults.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Methods<\/jats:bold>\n                    Cross\u2010sectional survey of a general adult population from Porto (all of whom were living with children involved in the International Study of Asthma and Allergies in Childhood\u2013phase three), during the year 2002, using a self\u2010administered questionnaire.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results<\/jats:bold>\n                    The prevalence of self\u2010reported drug allergy was 7.8% (181\/2309): 4.5% to penicillins or other \u03b2\u2010lactams, 1.9% to aspirin or other non\u2010steroidal anti\u2010inflammatory drugs (NSAIDs) and 1.5% to other drugs. In the group \u2018allergic to \u03b2\u2010lactams\u2019, the most frequently implicated drug was penicillin G or V (76.2%) followed by the association of amoxicillin and clavulanic acids (14.3%). In the group \u2018allergic to NSAIDs\u2019, acetylsalicylic acid (18.2%) and ibuprofen (18.2%) were the most frequently identified drugs, followed by nimesulide and meloxicam. Identification of the exact name of the involved drug was possible in less than one\u2010third of the patients, more often within the NSAID group (59.5%). Women were significantly more likely to claim a drug allergy than men (10.2% vs. 5.3%). The most common manifestations were cutaneous (63.5%), followed by cardiovascular symptoms (35.9%). Most of the reactions were immediate, occurring on the first day of treatment (78.5%). Only half of the patients were submitted to drug allergy investigations. The majority (86.8%) completely avoided the suspected culprit drug thereafter.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions<\/jats:bold>\n                    The results showed that self\u2010reported allergy to drugs is highly prevalent and poorly explored. Women seem to be more susceptible. \u03b2\u2010lactams and NSAIDs are the most frequently concerned drugs.\n                  <\/jats:p>","DOI":"10.1111\/j.1365-2222.2004.02070.x","type":"journal-article","created":{"date-parts":[[2004,10,12]],"date-time":"2004-10-12T05:10:51Z","timestamp":1097557851000},"page":"1597-1601","source":"Crossref","is-referenced-by-count":194,"title":["Self\u2010reported drug allergy in a general adult Portuguese population"],"prefix":"10.1111","volume":"34","author":[{"given":"E.","family":"Gomes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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