{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T04:43:56Z","timestamp":1763959436786},"reference-count":19,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2004,12,13]],"date-time":"2004-12-13T00:00:00Z","timestamp":1102896000000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Experimental Allergy"],"published-print":{"date-parts":[[2004,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:bold>Background\n\t\t\t\t\t<\/jats:bold> The prevalence of latex allergy in children is increasing worldwide. Previous multiple operations or atopic predisposition are known risk factors. In contrast, only sporadic cases of latex allergy have been reported in infants younger than 1 year, and the causative latex\u2010containing products or symptoms in young infants have not been studied in detail.<\/jats:p><jats:p><jats:bold>Objective\n\t\t\t\t\t<\/jats:bold> The purpose of this study is to analyse the symptoms and risk factors of latex allergy in young infants.<\/jats:p><jats:p><jats:bold>Methods\n\t\t\t\t\t<\/jats:bold> Cases of latex allergy in infants younger than 1 year were studied in detail. Clinical course, causative latex\u2010containing products were spotted and detailed analysis for latex allergy in patients and patients' parents was performed.<\/jats:p><jats:p><jats:bold>Conclusion\n\t\t\t\t\t<\/jats:bold> We report nine cases of latex allergy in infants younger than 1 year. None of them have any abnormality or previous operations. Six patients had atopic eczema\/dermatitis syndrome, one patient had bronchial asthma, whereas two patients had no overt allergic diseases. Symptoms of latex allergy were wheezing, swelling of face or lips, facial rash, or anaphylaxis, and causative latex\u2010containing products were teat, pacifier, nose cleaner, teether, balloon, or enema tube. All of the nine patients had positive skin prick test to latex and extract from causative latex\u2010containing products, whereas eight patients had positive serum latex\u2010specific IgE. Study for family history revealed that latex allergy was noted in either father or mother in six patients, in both father and mother in one patient, whereas no latex allergy was noted in parents in two patients. It should be noted that all of these patients had latex\u2010induced symptoms at home. Latex allergy in young infants may not be unusual. Physicians should be aware of latex allergy, and care should be taken to avoid contact with latex in young infants, especially when there is family history for latex allergy.<\/jats:p>","DOI":"10.1111\/j.1365-2222.2004.02128.x","type":"journal-article","created":{"date-parts":[[2004,12,13]],"date-time":"2004-12-13T11:16:00Z","timestamp":1102936560000},"page":"1910-1915","source":"Crossref","is-referenced-by-count":25,"title":["Latex allergy in infants younger than 1 year"],"prefix":"10.1111","volume":"34","author":[{"given":"H.","family":"Kimata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,12,13]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"53","article-title":"A cluster of anaphylactic reactions in children with spina bifida during general anaesthesia","volume":"94","author":"Kelly KJ","year":"1994","journal-title":"epidemiologic features, risk factors, and latex hypersensitivity"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.1998.tb00298.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.1999.00304.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1067\/mem.2002.122771"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.2001.00320.x"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/08964280309596170"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1992.tb05257.x"},{"issue":"10","key":"e_1_2_5_9_2","first-page":"1","article-title":"Skin tests used in type I allergy testing. 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