{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:24:11Z","timestamp":1791239051745,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2012,1,18]],"date-time":"2012-01-18T00:00:00Z","timestamp":1326844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Experimental Allergy"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Sleep is impaired in allergic rhinitis (<jats:styled-content style=\"fixed-case\">AR<\/jats:styled-content>) patients, with subsequent effects on daytime performance and health\u2010related quality of life (<jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content>). Sleep quality in <jats:styled-content style=\"fixed-case\">AR<\/jats:styled-content> has rarely been considered through validated tools and consensus classifications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate sleep quality and daytime somnolence in <jats:styled-content style=\"fixed-case\">AR<\/jats:styled-content> patients, and to estimate its relationship to disease severity according to Allergic Rhinitis and Its Impact on Asthma (<jats:styled-content style=\"fixed-case\">ARIA<\/jats:styled-content>) conventional and modified classifications, as well as in terms of <jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content> and comorbidities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Allergic rhinitis adult patients were evaluated through a prospective, observational, multicentre survey in <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>pain. Symptoms were assessed using the Total Symptoms Score (<jats:styled-content style=\"fixed-case\">TSS<\/jats:styled-content>), specific <jats:styled-content style=\"fixed-case\">QOL<\/jats:styled-content> by the Rhinitis Quality of Life Questionnaire (<jats:styled-content style=\"fixed-case\">RQLQ<\/jats:styled-content>), sleep quality by <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ittsburgh scale, and diurnal somnolence by a scale based on <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>pworth's, all recorded in a unique visit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 2275 patients were included. According to <jats:styled-content style=\"fixed-case\">ARIA<\/jats:styled-content> criteria, 50.2% had persistent and 49.8% intermittent rhinitis, whereas 87.6% were classified as moderate\u2010severe and 12.4% as mild; 52.8% had poor sleep quality, with a global median score for <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ittsburgh scale of 6 (normal\u00a0&lt;\u00a05) and 21.1% suffered from excessive diurnal somnolence. Correlation between <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ittsburgh scale and <jats:styled-content style=\"fixed-case\">RQLQ<\/jats:styled-content> was moderate (<jats:italic>r\u00a0<\/jats:italic>=\u00a00.54). Among symptoms, nasal obstruction and concomitant asthma mainly, contributed to bad sleep quality. In a logistic regression model, moderate\u2010severe rhinitis and nasal obstruction were all associated with a worse sleep quality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and clinical relevance<\/jats:title><jats:p>Sleep quality is altered in <jats:styled-content style=\"fixed-case\">AR<\/jats:styled-content> patients. Sleep quality was worse in moderate\u2010severe, and particularly in severe <jats:styled-content style=\"fixed-case\">AR<\/jats:styled-content>. Nasal obstruction and <jats:styled-content style=\"fixed-case\">RQLQ<\/jats:styled-content> deterioration are associated with a poorer sleep quality. Sleep impairment is common in allergic rhinitis, particularly in more severe forms. Nasal obstruction and concomitant asthma should be considered as contributing factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Capsule summary<\/jats:title><jats:p>This is a large epidemiological survey of patients with allergic rhinitis showing a strong relationship between disease severity, as assessed by a consensus classification, and sleep impairment, as measured by a validated sleep quality tool.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1365-2222.2011.03935.x","type":"journal-article","created":{"date-parts":[[2012,1,18]],"date-time":"2012-01-18T05:35:33Z","timestamp":1326864933000},"page":"1080-1087","source":"Crossref","is-referenced-by-count":69,"title":["Disease severity impairs sleep quality in allergic rhinitis (The <scp>SOMNIAAR<\/scp> study)"],"prefix":"10.1111","volume":"42","author":[{"given":"C.","family":"Col\u00e1s","sequence":"first","affiliation":[{"name":"Allergy Department Hospital Cl\u00ednico\u2010Instituto de Investigaci\u00f3n Sanitaria Arag\u00f3n Zaragoza Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Galera","sequence":"additional","affiliation":[{"name":"E.N.T. 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